ArticlebioRxiv : the preprint server for biology2025
The innate immune protein calprotectin incapacitates the bactericidal activity of β-lactam antibiotics.
Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
β-lactam antibiotics are widely used to treat bacterial infections, yet treatment failures frequently occur even without resistance. Here, we show that the innate immune protein calprotectin (CP), released by neutrophils and abundant at infection sites, induces tolerance to β-lactam antibiotics in
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