ArticlebioRxiv : the preprint server for biology2025
VaMiAnalyzer: An open source, python-based application for analysis of 3D
Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Background: Vasculogenic mimicry (VM) is the phenomenon whereby non-vascular tumor cells develop vascular-like structures. VM is linked to more aggressive tumor phenotypes including higher rates of metastasis and invasion and is potentially resistant to anti-angiogenic cancer therapies. VM is investigated Results: To address this limitation, we developed an open source, python-based application, VaMiAnalyzer, allowing straightforward quantification of several VM structural features. The application follows a two-step approach that optionally corrects and enhances the raw input images and then analyzes and quantifies the VM features. Conclusions: VaMiAnalyzer is stand-alone software that allows automated measurement of VM structural features from phase-contrast microscopy images. It produces results that are strongly consistent with manual counts but in a significantly shorter time, allowing speedy, non-biased analysis of VM from microscopy images.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.