ArticlebioRxiv : the preprint server for biology2025
Sex and Alkyladenine DNA Glycosylase Expression are Key Susceptibility Factors for NDMA-induced Mutations, Toxicity, and Cancer.
Jennifer E Kay, Joshua J Corrigan, Lindsay B Volk, Amanda L Armijo, Ilana S Nazari, Dorothea K Torous, Svetlana L Avlasevich, Robert G Croy, Dushan N Wadduwage, Stephen D Dertinger and 3 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
13 authors.
Jennifer E KayDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139.ORCID 0000-0001-5891-0689 Joshua J CorriganDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139.
Lindsay B VolkDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139.ORCID 0000-0001-8472-3836 Amanda L ArmijoDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139.ORCID 0000-0002-4868-4355 Ilana S NazariDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139.ORCID 0000-0003-3074-9488 Dorothea K TorousLitron Laboratories, Rochester, NY 14623, USA.
Svetlana L AvlasevichLitron Laboratories, Rochester, NY 14623, USA.
Robert G CroyDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139.
Dushan N WadduwageThe John Harvard Distinguished Science Fellows Program, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0002-0689-9454 Stephen D DertingerLitron Laboratories, Rochester, NY 14623, USA.
John M EssigmannDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139.ORCID 0000-0002-2196-5691 Leona D SamsonDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139.
Bevin P EngelwardDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139.ORCID 0000-0003-4322-3573 Funding
TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ENGELWARD, BEVIN P. · 1985 to 2020
$25.6MThe MIT Superfund Research Program: A Systems Approach for the Protection of Human Health from Hazardous ChemicalsP42ES027707 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Stuart S Levine · 2017 to 2026
$22.2MTRAINING GRANTS IN ENVIROMENTAL TOXICOLOGYT32ES007020 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ESSIGMANN, JOHN M · 1985 to 2024
$13.1MWide-Field Short-Wave Infrared (SWIR) multiphoton (MP) tissue imagingP41EB015871 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SO, PETER T. · 2012 to 2021
$11.3MIntra and Extra-Chromosomal Probes for Mutagenesis by CarcinogensR01CA080024 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ESSIGMANN, JOHN M · 1998 to 2025
$5.9MQuantifying early biomarkers of mammary carcinogenesis with multiplexed spatial biologyK01ES036182 · NIEHS · SILENT SPRING INSTITUTE · PI Jennifer Kay · 2024 to 2026
$469kNCI NIH HHS R01 CA080024NIBIB NIH HHS P41 EB015871NIEHS NIH HHS K01 ES036182NIEHS NIH HHS P30 ES002109NIEHS NIH HHS P42 ES027707NIEHS NIH HHS T32 ES007020
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
CancerDNA damageDNA RepairMutationsN-nitrosodimethylamineSex-related differences
Identifiers
PMID40463078
PMCPMC12132288
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390