Evidence map›Paper›PMID 40463036›Full record

ArticlebioRxiv : the preprint server for biology2025

Defect in hematopoiesis and embryonic lethality at midgestation of

Peng Xu, Rubia Isler Mancuso, Marianna Leonzino, Caroline J Zeiss, Diane S Krause, Pietro De Camilli

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Peng XuDepartment of Neuroscience, Yale University School of Medicine, New Haven, Connecticut 06510, USA.ORCID 0000-0001-5197-9560
Rubia Isler MancusoDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
Marianna LeonzinoDepartment of Neuroscience, Yale University School of Medicine, New Haven, Connecticut 06510, USA.ORCID 0000-0002-3277-1112
Caroline J ZeissDepartment of Comparative Medicine, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Diane S KrauseDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
Pietro De CamilliDepartment of Neuroscience, Yale University School of Medicine, New Haven, Connecticut 06510, USA.ORCID 0000-0001-9045-0723

Funding

Yale/NIDA Neuroproteomics Research CenterP30DA018343 · NIDA · YALE UNIVERSITY · PI ANGUS C. NAIRN, Kenneth Robert WILLIAMS · 2004 to 2026
$37.1M
Yale Cooperative Hematology Specialized Core CenterU54DK106857 · NIDDK · YALE UNIVERSITY · PI JOHN HWA, Diane S Krause · 2015 to 2026
$9.7M
MOLECULAR MECHANISMS IN SYNAPTIC VESICLE RECYCLINGR01NS036251 · NINDS · YALE UNIVERSITY · PI DE CAMILLI, PIETRO · 1997 to 2021
$4.7M
Molecular Mechanisms in Synaptic Vesicle RecyclingR37NS036251 · NINDS · YALE UNIVERSITY · PI DE CAMILLI, PIETRO · 2010 to 2016
$2.7M
High Performance Computing Instrumentation for the Yale Center for Genome AnalysisS10OD030363 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2022 to 2022
$1.2M
NIDA NIH HHS P30 DA018343NIDDK NIH HHS U54 DK106857NIH HHS S10 OD030363NINDS NIH HHS R01 NS036251NINDS NIH HHS R37 NS036251
6 · The paper itself

Abstract

VPS13 is the founding member of a family of proteins that mediate lipid transfer at intracellular membrane contact sites by a bridge-like mechanism. Mammalian genomes comprise 4

Identifiers

PMID40463036
PMCPMC12132566

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.