Evidence map›Paper›PMID 40463033›Full record

ArticlebioRxiv : the preprint server for biology2025

Role of channels in the

Pan Zhao, Fraser J Moss, Rossana Occhipinti, R Ryan Geyer, Dale E Huffman, Howard J Meyerson, Walter F Boron

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pan ZhaoDepartment of Physiology & Biophysics, Case Western Reserve University School of Medicine Cleveland, OH 44106.ORCID 0000-0002-1482-0857
Fraser J MossDepartment of Physiology & Biophysics, Case Western Reserve University School of Medicine Cleveland, OH 44106.ORCID 0000-0002-8519-6991
Rossana OcchipintiDepartment of Physiology & Biophysics, Case Western Reserve University School of Medicine Cleveland, OH 44106.ORCID 0000-0002-0519-7725
R Ryan GeyerDepartment of Physiology & Biophysics, Case Western Reserve University School of Medicine Cleveland, OH 44106.ORCID 0000-0001-9192-357X
Dale E HuffmanDepartment of Physiology & Biophysics, Case Western Reserve University School of Medicine Cleveland, OH 44106.ORCID 0000-0002-5619-8613
Howard J MeyersonDepartment of Pathology, Case Western Reserve University School of Medicine Cleveland, OH 44106.ORCID 0000-0001-5084-6643
Walter F BoronDepartment of Physiology & Biophysics, Case Western Reserve University School of Medicine Cleveland, OH 44106.ORCID 0000-0003-4741-7287

Funding

Multi-scale modeling of gas transport through channels in living cellsU01GM111251 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI BORON, WALTER F, SOMERSALO, ERKKI JAAKKO · 2015 to 2019
$2.9M
Mechanisms of oxygen off-loading from red blood cells in murine models of human diseaseR01HL160857 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI BORON, WALTER F · 2022 to 2025
$2.6M
Acid secretion and intracellular pH regulation in proximal-tubule cellsK01DK107787 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI OCCHIPINTI, ROSSANA · 2015 to 2019
$541k
NHLBI NIH HHS R01 HL160857NIDDK NIH HHS K01 DK107787NIGMS NIH HHS U01 GM111251
6 · The paper itself

Abstract

Many have believed that oxygen

Indexed as

Aquaporin 1DIDS (4,4’-diisothiocyanatostilbene-2,2’-disulfonate)genetic deletionpCMBS (p-chloromercuribenzenesulfonate)Rhesus (Rh) complex

Identifiers

PMID40463033
PMCPMC12132281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.