Evidence map›Paper›PMID 40463025›Full record

ArticlebioRxiv : the preprint server for biology2025

SARM1 is an essential component of neuronal Parthanatos.

Tong Wu, Liya Yuan, Yo Sasaki, William Buchser, A Joseph Bloom, Aaron DiAntonio, Jeffrey Milbrandt

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Tong WuDepartment of Genetics, Washington University School of Medicine, St. Louis, MO, USA 63110.ORCID 0000-0001-9121-2495
Liya YuanDepartment of Genetics, Washington University School of Medicine, St. Louis, MO, USA 63110.
Yo SasakiDepartment of Genetics, Washington University School of Medicine, St. Louis, MO, USA 63110.
William BuchserDepartment of Genetics, Washington University School of Medicine, St. Louis, MO, USA 63110.ORCID 0000-0002-6675-6359
A Joseph BloomDepartment of Genetics, Washington University School of Medicine, St. Louis, MO, USA 63110.ORCID 0000-0002-6731-5539
Aaron DiAntonioNeedleman Center for Neurometabolism and Axonal Therapeutics, St. Louis, MO, USA 63110.ORCID 0000-0002-7262-0968
Jeffrey MilbrandtDepartment of Genetics, Washington University School of Medicine, St. Louis, MO, USA 63110.ORCID 0000-0002-5477-7689

Funding

DISSECTION OF SARM1-INDUCED AXON DEGENERATION AND CELL DEATHR01NS087632 · NINDS · WASHINGTON UNIVERSITY · PI Aaron Diantonio, JEFFREY D MILBRANDT · 2014 to 2026
$6.4M
Regulation of axonal degeneration by the DLK kinaseR37NS065053 · NINDS · WASHINGTON UNIVERSITY · PI Aaron Diantonio · 2020 to 2026
$4.3M
REGULATION OF AXONAL DEGENERATION BY THE DLK KINASER01NS065053 · NINDS · WASHINGTON UNIVERSITY · PI DIANTONIO, AARON · 2010 to 2019
$3.3M
The role of SARM1 in neuroinflammation-mediated axonal damageR01NS133348 · NINDS · WASHINGTON UNIVERSITY · PI Aaron Diantonio, JEFFREY D MILBRANDT · 2024 to 2026
$1.7M
NINDS NIH HHS R01 NS065053NINDS NIH HHS R01 NS087632NINDS NIH HHS R01 NS133348NINDS NIH HHS R37 NS065053
6 · The paper itself

Abstract

The NAD

Identifiers

PMID40463025
PMCPMC12132571

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.