Evidence map›Paper›PMID 40462972›Full record

ArticlebioRxiv : the preprint server for biology2025

Induced tolerance to UV stress drives survival heterogeneity in isogenic

Shunsuke Ichikawa, Midai Tanoue, Junto Takeuchi, Eri Matsuo, Yasuhito Shimada, Abhyudai Singh

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Shunsuke IchikawaFaculty of Education, Mie University, 1577 Kurimamachiya-cho Tsu, Mie, 514-8507, Japan.ORCID 0000-0003-2935-004X
Midai TanoueFaculty of Education, Mie University, 1577 Kurimamachiya-cho Tsu, Mie, 514-8507, Japan.
Junto TakeuchiFaculty of Education, Mie University, 1577 Kurimamachiya-cho Tsu, Mie, 514-8507, Japan.
Eri MatsuoFaculty of Education, Mie University, 1577 Kurimamachiya-cho Tsu, Mie, 514-8507, Japan.
Yasuhito ShimadaZebrafish Research Center, Mie University, 1577 Kurimamachiya-cho Tsu, Mie, 514-8507, Japan.ORCID 0000-0002-4111-8262
Abhyudai SinghDepartment of Electrical and Computer Engineering, Biomedical Engineering and Mathematical Sciences, Center of Bioinformatics and Computational Biology, University of Delaware, Newark, Delaware 19716, USA.ORCID 0000-0002-1451-2838

Funding

Generalized fluctuation test for deciphering phenotypic switching within cell populationsR35GM148351 · NIGMS · UNIVERSITY OF DELAWARE · PI Abhyudai Singh · 2023 to 2026
$1.6M
NIGMS NIH HHS R35 GM148351
6 · The paper itself

Abstract

The emergence of transiently tolerant bacterial subpopulations challenges our understanding of stress tolerance mechanisms. While much is known about antibiotic tolerance, it remains unclear whether similar mechanisms contribute to survival under ultraviolet (UV) stress. Here, we employed a modified Luria-Delbrück fluctuation test to investigate the presence of pre-existing UV-tolerant subpopulations in

Indexed as

Escherichia coliModified Luria-Delbrück fluctuation testpersisterprimed cellsultraviolet light irradiation

Identifiers

PMID40462972
PMCPMC12132193

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.