Evidence map›Paper›PMID 40462924›Full record

ArticlebioRxiv : the preprint server for biology2025

Frog-killing chytrid fungi deploy different strategies to regulate intracellular pressure in cell types that have or lack a cell wall.

Sarah Prostak, Katrina B Velle, Lillian K Fritz-Laylin

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Sarah ProstakDepartment of Biology, University of Massachusetts Amherst, Amherst, MA.
Katrina B VelleDepartment of Biology, University of Massachusetts Dartmouth, North Dartmouth, MA, 02747.ORCID 0000-0002-9985-9522
Lillian K Fritz-LaylinDepartment of Biology, University of Massachusetts Amherst, Amherst, MA.ORCID 0000-0002-9237-9403

Funding

Defining cytoskeletal mechanisms driving cell motility in NaegleriaR00GM147656 · NIGMS · UNIVERSITY OF MASSACHUSETTS DARTMOUTH · PI Katrina Velle · 2024 to 2026
$747k
NIGMS NIH HHS R00 GM147656
6 · The paper itself

Abstract

Cell morphogenesis is crucial for the physiology of animals and fungi alike. While animals typically shape their cells using the actin cytoskeleton, fungi control cell shape through polarized deposition of new cell wall material, which is inflated by intracellular osmotic "turgor" pressure. Understanding where and when these mechanisms evolved is essential for understanding the evolution of cell morphogenesis. To this end, we study chytrid fungi, which have a cell type that lacks a cell wall (the "zoospore") and a cell type that has a cell wall (the "sporangium"). While chytrid sporangia rely on polarized cell wall growth to control shape, we previously showed that the "frog-killing" chytrid fungus

Identifiers

PMID40462924
PMCPMC12132441

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.