ArticleFrontiers in psychiatry2025
Effect of mindfulness group therapy on maternal psychological distress and perinatal outcomes in twin pregnancy: a randomized controlled trial.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- The Effect of a Mindfulness-Based Stress Reduction (MBSR) Program on Quality of Life, Life Satisfaction, Sleep Quality, and Mental Well-Being in Menopausal Women: A Randomized Controlled Trial.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2026Trial
- A Narrative Review of Implementing Nonpharmacological Interventions for Antenatal Depression in Low Resource Settings With Implications for Palestine.Depression and anxiety · 2026Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Psychosocial stress, depression, and anxiety are prevalent during pregnancy and can be associated with adverse birth outcomes. This study aimed to evaluate the effectiveness of an online Mindfulness Group Therapy (MGT) program in improving perinatal maternal psychological distress and perinatal outcomes among women with twin pregnancies. Methods: In this randomized controlled trial, 120 women carrying twins were assigned to MGT groups (6-week, 120 minutes of mindfulness intervention weekly) or control groups (usual perinatal care and health education). The primary outcomes were maternal psychological distress, including depression, anxiety, stress, and mindfulness measured by the Edinburgh Postnatal Depression Scale, State Anxiety Inventory, Perceived Stress Scale, and Five Facet Mindfulness Questionnaire at three points: baseline, post-intervention and time one month postpartum. Secondary outcomes included maternal pregnancy outcomes and neonatal outcomes. Results: A total of 109 women with twin pregnancies completed the intervention. The intervention significantly and effectively prevented the worsening of postpartum depression symptoms in women with twin pregnancies, improved mindfulness, and reduced perceived stress (P < 0.05). Significant differences were observed at both post-intervention, and 1-month post-delivery (P < 0.05). However, no significant differences were found in anxiety scores (P > 0.05). Intention-to-treat analysis further revealed that the intervention had a significant effect on reducing postpartum depressive symptoms (P < 0.05), even when considering participants who did not complete the entire study process. In terms of pregnancy outcomes, a significant difference was found between the intervention and control groups in the incidence of low birth weight (P<0.05). Conclusion: MGT proves potentially effective in reducing perinatal stress, preventing prenatal depression, and decreasing the incidence of low-birth-weight infants in twin pregnancies. These findings support the integration of group mindfulness interventions into prenatal mental health care to mitigate prenatal depression among women expecting twins. Clinical Trial Registration: https://www.chictr.org.cn/showproj.html?proj=131787, identifier ChiCTR2100050091.
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