Evidence map›Paper›PMID 40462777›Full record

ArticleCureus2025

Surgical Management of a Spontaneous Hepatocellular Carcinoma Rupture in a Non-cirrhotic Liver: A Case Report.

Maria Isabel Manso, Henrique Morais, Ruben Martins, Mafalda Machado, Gildasio Martins Dos Santos

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria Isabel MansoGeneral Surgery Department, Unidade Local de Saúde (ULS) Algarve, Faro, PRT.
Henrique MoraisGeneral Surgery Department, Hospital de Loulé, Loulé, PRT.
Ruben MartinsGeneral Surgery Department, Hospital de Loulé, Loulé, PRT.
Mafalda MachadoRadiology Department, Centro Hospitalar Universitário do Algarve, Faro, PRT.
Gildasio Martins Dos SantosGeneral Surgery Department, Unidade Local de Saúde (ULS) Algarve, Faro, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous rupture of hepatocellular carcinoma (HCC) is an uncommon and life-threatening condition that poses significant diagnostic and therapeutic challenges. This report describes the case of a 78-year-old man with no prior history of liver disease who presented with acute abdominal pain and hemoperitoneum. Imaging revealed a ruptured exophytic HCC lesion in hepatic segment II, which was confirmed during laparotomy. The patient underwent successful segment II resection following stabilization, and histopathological analysis confirmed a moderately differentiated HCC in a non-cirrhotic liver. The postoperative course was uneventful. This case highlights the importance of timely diagnosis, tailored management strategies, and multidisciplinary care in addressing the complexities of spontaneous HCC rupture, particularly in patients without underlying liver disease.

Indexed as

acute care surgeryhemoperitoneumhepatocellular carcinoma (hcc)liver resectionnon-cirrhotic liver

Identifiers

PMID40462777
PMCPMC12130909

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.