ReviewRegenerative medicine2025
Engineering organoids for dental pulp tissue regeneration and functional reconstruction.
Review in Regenerative medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organoids, which replicate the three-dimensional architecture and physiological functions of native organs, have emerged as a groundbreaking tool with significant therapeutic potential for tissue regeneration and functional reconstruction. Despite their broad applications in various fields, research on dental pulp organoids and their use in regenerative therapies remains in its early stages, presenting both opportunities and challenges. To advance the understanding of organoid technology and facilitate its translation into pulp regenerative medicine, this review provided a comprehensive overview of organoids, encompassing their developmental history, self-organization mechanisms, fundamental definitions, and current applications. Building on this foundation, we highlighted recent progress in oral and maxillofacial organoid research, with a particular focus on the construction of dental pulp organoids. Additionally, we systematically summarized the commonly employed construction methods and explored innovative bioengineering strategies that hold promise for future applications. Finally, we critically evaluated the existing challenges in applying organoid technology to pulp tissue regeneration and functional reconstruction, while proposing potential solutions to overcome these barriers. This review aimed to provide valuable insights and inspire further research in this rapidly evolving field.
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Registered trials
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