SynthesisBrain and behavior2025
Placebo and Nocebo Effects in Motor Performance: An Overview of Reviews.
Synthesis in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectivesTo assess and synthesize the effect size and quality of the literature on the placebo and nocebo effects on motor performance and motor-related perceptive responses.
designUmbrella review. DATA SOURCES: Medline, Embase, Lilacs, Cochrane Database of Systematic Reviews for peer-reviewed literature, PROSPERO for protocols, and the Open Access Theses and Dissertations for gray literature. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Population-human participants with varied health conditions; intervention: placebo; control: no treatment or active intervention; outcome: motor performance (primary) and perceptual variables (secondary); study design-ystematic reviews with or without meta-analysis.
resultsIn total, 3432 records were gathered from searches, resulting in 13 eligible reviews after screening. These reviews encompassed 247 original studies, with 221 focusing on the placebo effect and 26 on the nocebo effect. Among all eligible systematic reviews, five conducted meta-analysis with 5036 participants, and one provided a summary of effect sizes reported by the original studies with 1215 participants. The reviews reported small to large effects of placebo (SMD = 0.09-0.93) and nocebo (SMD = 0.37-1.20), and only two conducted the GRADE assessment.
conclusionWe found varied placebo and nocebo effects on motor performance, likely due to the poor quality of the methodology used by most reviews, highlighting the need for well-conducted systematic reviews on the placebo and nocebo phenomena.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.