Evidence map›Paper›PMID 40462492›Full record

ArticleJournal of the American Chemical Society2025

Introducing Prism[4]arene: A Macrocycle with Enantiomerically Resolvable Inherent Chirality and Intriguing Chiroptical Properties.

Paolo Della Sala, Carmen Talotta, Margherita De Rosa, Stefano Superchi, Ernesto Santoro, Silvano Geremia, Neal Hickey, Marco Fusè, Sergio Abbate, Giuseppe Mazzeo and 2 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Paolo Della SalaLaboratory of Supramolecular Chemistry, Dipartimento di Chimica e Biologia "A. Zambelli", Università di Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Salerno, Italy.ORCID 0000-0002-6379-0332
Carmen TalottaLaboratory of Supramolecular Chemistry, Dipartimento di Chimica e Biologia "A. Zambelli", Università di Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Salerno, Italy.ORCID 0000-0002-2142-6305
Margherita De RosaLaboratory of Supramolecular Chemistry, Dipartimento di Chimica e Biologia "A. Zambelli", Università di Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Salerno, Italy.ORCID 0000-0001-7451-5523
Stefano SuperchiDipartimento di Scienze di Base e Applicate, Università della Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0002-7265-1625
Ernesto SantoroDipartimento di Scienze di Base e Applicate, Università della Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Silvano GeremiaCentro di Eccellenza in Biocristallografia, Dipartimento di Scienze Chimiche e Farmaceutiche, Università di Trieste, Via L. Giorgieri 1, I-34127 Trieste, Italy.ORCID 0000-0002-0711-5113
Neal HickeyCentro di Eccellenza in Biocristallografia, Dipartimento di Scienze Chimiche e Farmaceutiche, Università di Trieste, Via L. Giorgieri 1, I-34127 Trieste, Italy.ORCID 0000-0003-1271-5719
Marco FusèDipartimento di Medicina Molecolare e Traslazionale, Università di Brescia, Viale Europa 11, 25123 Brescia, Italy.ORCID 0000-0003-0130-5175
Sergio AbbateDipartimento di Medicina Molecolare e Traslazionale, Università di Brescia, Viale Europa 11, 25123 Brescia, Italy.ORCID 0000-0001-9359-1214
Giuseppe MazzeoDipartimento di Medicina Molecolare e Traslazionale, Università di Brescia, Viale Europa 11, 25123 Brescia, Italy.ORCID 0000-0002-3819-6438
Giovanna LonghiDipartimento di Medicina Molecolare e Traslazionale, Università di Brescia, Viale Europa 11, 25123 Brescia, Italy.ORCID 0000-0002-0011-5946
Carmine GaetaLaboratory of Supramolecular Chemistry, Dipartimento di Chimica e Biologia "A. Zambelli", Università di Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Salerno, Italy.ORCID 0000-0002-2160-8977

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents the first report of an inherently chiral prismarene with resolved enantiomers. Prism[4]arenes, synthesized via a thermodynamic template approach using a tailor-made selective cation, effectively maintain their chirality due to their strained macrorings and narrow annuli, which prevent the flipping of naphthalene rings. The solid-state structure of the synthesized

Identifiers

PMID40462492
PMCPMC12186475

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.