ArticlePublic health nutrition2025
Contemporary factors affecting serum 25-hydroxyvitamin D concentrations in Chinese children aged 2-6 years.
Article in Public health nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveWe investigated vitamin D (VitD) nutritional status in children aged 2-6 years to provide a basis for prevention and intervention strategies for VitD deficiency (VitDD) in Chinese children.
designFrom November 2018 to September 2019, a total of 2192 healthy children aged 2-6 years were enrolled. The serum 25-hydroxyvitamin D (25(OH)D) concentrations were measured by liquid chromatography tandem MS.
settingTwelve jurisdictions in eight provinces and cities across northern and southern China were selected through stratified cluster sampling.
participants2192 children aged 2-6 years were enrolled.
results(1) A serum 25(OH)D concentration of 23·87 (sd 8·24) ng/ml, a VitDS rate of 65·2 %, an insufficiency rate of 29·6 % and a deficiency rate of 5·2 % were noted. (2) Age (OR = 2·22, 95 % CI 1·86, 2·64) and spring (OR = 1·35, 95 % CI 0·91, 2·01) are risk factors for VitDD and VitDI. The male (OR = 0·68, 95 % CI 0·52, 0·90), the temperature (OR = 0·89, 95 % CI 0·86, 0·93), summer (OR = 0·25, 95 % CI 0·09, 0·68), autumn (OR = 0·26, 95 % CI 0·09, 0·74) the intake of VitD supplements (OR = 0·08, 95 % CI 0·03, 0·28), the intake frequency of dairy products (OR = 0·86, 95 % CI 0·78, 0·96) and egg products (OR = 0·83, 95 % CI 0·74, 0·93) are protective factors for VitDD and VitDI.
conclusionVitDD in children aged 2-6 years is still prevalent in China, but the influencing factors of VitD nutrition have changed. Latitude is not the main factor in the 25(OH)D concentrations of children aged 2-6 years; temperature, intake of eggs and dairy products and sampling season have more obvious impacts.
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