ArticleJournal of health, population, and nutrition2025
Assessment of quality of life in visceral leishmaniasis patients coinfected with HIV: a comparative study in Bihar, India.
Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThis study was aimed to evaluates the quality of life using WHOQOL-BREF in VL patients co-infected with HIV in Bihar, India.
methodsThis cross-sectional study enrolled 240 participants: 60 HIV-VL co-infected, 60 HIV, 60 VL and 60 healthy individuals. Socio-demographic data and QOL assessments used the Hindi WHOQOL-BREF questionnaire. The data were compared using the chi-square test, One-Way ANOVA followed by Tukey's post-hoc Test. Generalised linear regression was performed for analyses of predictors of QOL, as well as the socio-economic status was determined by using the Modified Kuppuswamy socio-economic Scale 2022.
resultsHIV-VL co-infected patients reported significantly lower QOL scores across all domains (physical, psychological, social relationships, and environmental) compared to healthy individuals (p < 0.05). Notably, psychological (12.17 ± 1.17), social relationship (5.90 ± 1.16), and environmental (14.10 ± 1.68) domains were severely impacted in HIV-VL coinfection in contrast to HIV (p < 0.05) and VL (p < 0.05).
conclusionHIV-VL co-infection profoundly affects quality of life, emphasizing the need for targeted interventions addressing psychological, social and environmental well-being. Future research should prioritize strategies improving QOL and assessing long-term treatment effects in HIV-VL co-infection.
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