Evidence map›Paper›PMID 40462125›Full record

ArticleWorld journal of surgical oncology2025

A modified liver retraction method decreases liver dysfunction after laparoscopic gastrectomy.

Hao-Jie Li, Lang Zhou, Wei-Han Zhang, Kai Liu, Kun Yang, Jian-Kun Hu, Xiao-Long Chen

Abstract read
In one paragraph

Article in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Hao-Jie LiDepartment of General Surgery, Gastric Cancer Center & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang Street, Chengdu, Sichuan Province, 610041, China.
Lang ZhouDepartment of General Surgery, Gastric Cancer Center & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang Street, Chengdu, Sichuan Province, 610041, China.
Wei-Han ZhangDepartment of General Surgery, Gastric Cancer Center & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang Street, Chengdu, Sichuan Province, 610041, China.
Kai LiuDepartment of General Surgery, Gastric Cancer Center & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang Street, Chengdu, Sichuan Province, 610041, China.
Kun YangDepartment of General Surgery, Gastric Cancer Center & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang Street, Chengdu, Sichuan Province, 610041, China. 13658002983@163.com.
Jian-Kun HuDepartment of General Surgery, Gastric Cancer Center & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang Street, Chengdu, Sichuan Province, 610041, China.
Xiao-Long ChenDepartment of General Surgery, Gastric Cancer Center & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang Street, Chengdu, Sichuan Province, 610041, China. 626290977@qq.com.

Funding

1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University (ZYJC21006) ZYJC21006
6 · The paper itself

Abstract

backgroundIn laparoscopic gastrectomy, liver retraction is an important procedure to obtain a sufficient operative view to ensure the quality of surgery. However, postoperative liver dysfunction is frequently encountered after liver retraction. This study aims to explore the effect of a modified liver retraction method (MLR) we designed on the postoperative liver function of patients receiving laparoscopic radical gastrectomy.

methodsThe data of patients who underwent laparoscopic gastrectomy by a single surgical group from August 2021 to April 2024 were retrospectively analyzed. These patients underwent laparoscopic gastrectomy without liver biopsy, partial hepatectomy, or cholecystectomy. We divided 218 patients into two groups based on the liver retraction method used, either MLR group or the simple liver retraction(SLR) group. In MLR group, we used rubber tubes and 2 - 0 proleneTM creating a "Ω-shaped" appearance to retract the liver, and in SLR group, only 2 - 0 proleneTM was used. Operative and postoperative outcomes were assessed, including the values of serum liver enzymes and total bilirubin within 5 days after surgery.

resultsThe results showed that there was no significant difference in operation time between MLR group and SLR group (317 ± 47 min vs. 318 ± 55 min, p = 0.91). Compared with SLR group, MLR group had a lower rate of liver dysfunction (serum liver enzymes or total bilirubin increased more than 2 times) after the operation (16.9% vs. 36.7%, p < 0.01), less use of the hepatoprotective drugs (4.2% vs. 17.7%, p < 0.01) and more No.7 lymph nodes. In subgroup analysis, we found that the rate of liver dysfunction was significantly different between MLR and SLR groups in distal gastrectomy (12.8% vs. 32.4%, p = 0.01).

conclusionThe operation time of MLR was similar to SLR group, but the rate of liver dysfunction, and use of hepatoprotective drugs in MLR group was significantly lower than SLR group. MLR is recommended in laparoscopic gastrectomy and particularly in distal gastrectomy.

Indexed as

GastrectomyLaparoscopyLiverLiver DiseasesPostoperative ComplicationsStomach NeoplasmsAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedOperative TimePrognosisRetrospective StudiesGastrectomyLaparoscopyStomach neoplasms

Identifiers

PMID40462125
PMCPMC12131373

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.