Evidence map›Paper›PMID 40462058›Full record

Trial reportBMC musculoskeletal disorders2025

Effectiveness of stationary cycling with electromyographic biofeedback on neuromuscular control and function in individuals with knee osteoarthritis: a feasibility study.

Chia-Ming Chang, Huynh Chung, Horng-Chaung Hsu, Li-Tzu Chen, Ruei-Yi Lin, Hsiu-Chen Lin

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03484910 (Application of Biofeedback Combined With Cycling Exercise in the Patients With Osteoarthritis of the Knee), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03484910 nacompletednot on this map

Application of Biofeedback Combined With Cycling Exercise in the Patients With Osteoarthritis of the Knee

TypeinterventionalSponsorChina Medical University HospitalRan2018 to 2020Enrolled23ConditionsExercise Therapy, Osteoarthritis Of Knee, BiofeedbackArmsExercise therapy
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chia-Ming Chang *Department of Physical Therapy & Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan.
Huynh Chung *Department of Physical Therapy & Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan.
Horng-Chaung HsuDepartment of Orthopedics, China Medical University Hospital, Taichung, Taiwan.
Li-Tzu ChenDepartment of Physical Therapy & Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan.
Ruei-Yi LinDepartment of Physical Therapy & Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan.
Hsiu-Chen LinDepartment of Physical Therapy & Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan. hclin@mail.cmu.edu.tw.

Funding

China Medical University, Taiwan CMU110-N-01China Medical Universuty Hospital DMR-107-131National Science and Technology Council MOST 107-2410-H-039 -005
6 · The paper itself

Abstract

backgroundTo evaluate the effects of stationary cycling with electromyographic (EMG) biofeedback on neuromuscular control and function in individuals with knee osteoarthritis (OA).

methodsFourteen knee OA patients were randomized into two groups: cycling with EMG biofeedback of the vastus medialis (EBF group) and cycling without biofeedback (Cycling group). Both groups underwent a six-week cycling program, 30 min per session, twice a week. Outcomes were measured at baseline and post-training. Knee pain and function were assessed using the Visual Analog Scale and the Knee Injury and Osteoarthritis Outcome Score (KOOS). Quadriceps strength and endurance were evaluated with an isokinetic machine, and muscle activation was recorded using a wireless EMG system. A two-way mixed-model analysis of variance (ANOVA) was used to assess the differences between sides and groups. For outcomes that were not normally distributed, the non-parametric Mann-Whitney U test was performed.

resultsBoth groups showed improvements in knee pain and function, with no significant differences between groups. Muscle strength remained largely unchanged, but the endurance was improved on the contralateral side (p = 0.038, η

conclusionsA six-week cycling program can alleviate pain and enhance knee function. EMG biofeedback of the vastus medialis significantly changed the neuromuscular control in the rectus femoris and vastus lateralis during cycling. Therefore, this study demonstrated that stationary cycling combined with electromyographic biofeedback training can enhance neuromuscular control of the quadriceps and potentially improve functional performance in patients with OA.

trial registrationClinicalTrials.gov identifier, NCT03484910 (registered at March 31st, 2018).

Indexed as

BicyclingBiofeedback, PsychologyElectromyographyExercise TherapyOsteoarthritis, KneeQuadriceps MuscleAgedFeasibility StudiesFemaleHumansKnee JointMaleMiddle AgedMuscle StrengthPain MeasurementTreatment OutcomeBiofeedbackExerciseNeuromuscular controlOsteoarthritisVastus medialis

Identifiers

PMID40462058
PMCPMC12131401

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.