Evidence map›Paper›PMID 40462042›Full record

ArticleBMC cancer2025

Association between triglyceride-glucose index and hypertension in adults with cancer from NHANES 2005-2018: a cross-sectional study.

Gangping Li, Di Zhang, Minghui Li, Fangfang Yuan, Yongqi Wang, Yuewen Fu

Abstract read
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Gangping LiDepartment of Hematology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China.
Di ZhangDepartment of Medical Records Management Department, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China.
Minghui LiDepartment of Hematology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China.
Fangfang YuanDepartment of Hematology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China.
Yongqi WangDepartment of Hematology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China.
Yuewen FuDepartment of Hematology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China. zlyyfuyuewen1480@zzu.edu.cn.

Funding

Henan Province Science and Technology Research and Development Plan LHGJ20220188Henan Province Young and Middle-aged Talent Plan Project YXKC2022046
6 · The paper itself

Abstract

backgroundInsulin resistance (IR) is linked to hypertension development.The triglyceride-glucose (TyG) index is a proposed alternative biochemical marker for IR. This study aimed to explore the relationship between TyG and hypertension in adults with cancer.

methodsA cross-sectional study was conducted involving 1,222 cancer adults patients from the NHANES dataset (2005-2018). Demographics, medical history, lifestyle factors, and lab tests were assessed. Multivariable logistic regression, subgroup analysis, and smooth curve-fitting techniques were used.

resultsAmong 1,222 eligible participants, 775 (56.29%) had hypertension. When TyG was assessed as a continuous variable, higher TyG levels were significantly associated with increased hypertension prevalence (OR, 1.51; 95% CI, 1.09-2.11; p = 0.015) after adjusting for covariates. When TyG was analyzed as quartiles, compared to individuals with lower TyG Q1 (7.0-8.3), the adjusted OR values for TyG and hypertension in Q2 (8.3-8.7), Q3 (8.7-9.1), and Q4 (9.1-10.7) were 1.32 (95% CI: 0.85-2.06, p = 0.022), 1.63 (95% CI: 1.01-2.64, p = 0.043), and 1.68 (95% CI: 1.09-2.84, p = 0.041), respectively. The data were stratified by age, sex, marital status, education level, and family income. Stratified analysis revealed no significant interactions among subgroups (all p-Values > 0.05). Analysis using restricted cubic splines(RCS) suggested a linear relationship between TyG and hypertension in adults with cancer.

conclusionsHigher TyG levels are associated with an increased risk of hypertension in adults with cancer.

Indexed as

Blood GlucoseHypertensionNeoplasmsTriglyceridesAdultAgedBiomarkersCross-Sectional StudiesFemaleHumansInsulin ResistanceMaleMiddle AgedNutrition SurveysPrevalenceRisk FactorsBiomarkersBlood GlucoseTriglyceridesCancerCross- sectional studyHypertensionNHANESTriglyceride-glucoseindex

Identifiers

PMID40462042
PMCPMC12135444

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.