Evidence map›Paper›PMID 40462016›Full record

Trial reportBMC pregnancy and childbirth2025

Impact of health literacy and primary language on the decision to pursue trial of labor after prior cesarean delivery.

Daisy Leon-Martinez, Christine Dehlendorf, Molly Zeme, W John Boscardin, Anjali J Kaimal, William A Grobman, Miriam Kuppermann

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daisy Leon-MartinezDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California-San Francisco, 490 Illinois Street, Floor 10, San Francisco, CA, 94143, USA. Daisy.Leon-Martinez@ucsf.edu.
Christine DehlendorfDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California-San Francisco, 490 Illinois Street, Floor 10, San Francisco, CA, 94143, USA.
Molly ZemeSchool of Medicine, University of California-San Francisco, 533 Parnassus Ave., San Francisco, CA, 94143, USA.
W John BoscardinDepartment of Epidemiology and Biostatistics, University of California-San Francisco, 3333 California Street, #220G, San Francisco, CA, 94118, USA.
Anjali J KaimalDepartment of Obstetrics and Gynecology, University of South Florida Morsani College of Medicine, 2 Tampa General Circle, 6th Floor, Tampa, FL, 33606, USA.
William A GrobmanDepartment of Obstetrics and Gynecology, The Warren Alpert Medical School of Brown University, 101 Dudley St., Providence, RI, 02905, USA.
Miriam KuppermannDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California-San Francisco, 490 Illinois Street, Floor 10, San Francisco, CA, 94143, USA.

Funding

Effect of a patient-centered decision app on TOLAC: An RCTR01HD078748 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KUPPERMANN, MIRIAM · 2014 to 2018
$3.2M
NICHD NIH HHS R01 HD078748
6 · The paper itself

Abstract

backgroundBoth a trial of labor after cesarean (TOLAC) and elective repeat cesarean delivery (ERCD) are reasonable choices after a cesarean delivery, with differing risks and benefits. This study explores the impact of patient health literacy and primary language on the decision to pursue a TOLAC and on decision quality.

methodsThis is a secondary analysis of the Prior Cesarean Decision (PROCEED) trial, which examined the effect of a patient-centered decision support tool on rates of TOLAC and decision quality. Logistic regression was performed to estimate the association of limited health literacy (Newest Vital Sign score ≤4/6) and non-English primary language (NEPL) with TOLAC. Decision quality was assessed by calculating mean scores for decision-quality scales and using linear regression to estimate adjusted mean differences (aMD) by health literacy and NEPL.

resultsAmong 1455 participants, 44.6% underwent TOLAC, and 71.0% of those with a TOLAC had a vaginal birth after cesarean (VBAC). Limited health literacy was associated with lower odds of TOLAC (aOR 0.60, 95% CI [0.38, 0.93]). For decision quality, limited health literacy was associated with similar scores for decisional conflict, shared decision-making, decision self-efficacy and decision satisfaction, but lower knowledge scores (3.9 vs. 5.4; aMD -0.7, 95% CI [-1.0, -0.5]). Compared to participants whose primary language was English (n=1043), those with NEPL (n=255) had similar odds of TOLAC (aOR 1.08, 95% CI [0.69, 1.68]), but greater decisional conflict (20.9 vs. 16.7; aMD 3.9, 95% CI [1.4, 6.3]) and lower decision self-efficacy (88.6 vs. 90.9; aMD -3.3, 95% CI [-5.6, -1.1]) and decision satisfaction (4.6 vs. 4.7; aMD -0.1, 95% CI [-0.2, 0.0]).

conclusionsIn this study of pregnant people with a prior cesarean and no prior VBAC, those with limited health literacy had lower odds of TOLAC and lower knowledge scores about risks and benefits of TOLAC vs. ERCD. While those with NEPL had similar odds of TOLAC, they had lower decision quality scores compared to those with those with English as a primary language. These findings indicate factors that may result in less effective counseling related to delivery options after prior cesarean and may contribute to differences in approach to delivery and decision quality.

Indexed as

Health LiteracyLanguagePregnant PeopleTrial of LaborVaginal Birth after CesareanAdultCesarean Section, RepeatDecision MakingFemaleHealth Knowledge, Attitudes, PracticeHumansLogistic ModelsPregnancySecondary Data AnalysisSelf EfficacyDecision qualityDecision satisfactionDecision self-efficacyHealth literacyPrimary languageShared decision-makingTOLACTrial of labor after cesareanVaginal birth after cesareanVBAC

Identifiers

PMID40462016
PMCPMC12131817

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.