Evidence map›Paper›PMID 40462000›Full record

ArticleBMC bioinformatics2025

Pytrf: a python package for finding tandem repeats from genomic sequences.

Lianming Du, Dalin Sun, Jiahao Chen, Xinyi Zhou, Kelei Zhao, Qianglin Zeng, Nan Yang

Abstract read
In one paragraph

Article in BMC bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Finding low-complexity DNA sequences with longdust.Bioinformatics (Oxford, England) · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lianming DuAntibiotics Research and Re-Evaluation Key Laboratory of Sichuan Province, Institute for Advanced Study, Chengdu University, Chengdu, 610106, China.
Dalin SunAntibiotics Research and Re-Evaluation Key Laboratory of Sichuan Province, Institute for Advanced Study, Chengdu University, Chengdu, 610106, China.
Jiahao ChenAntibiotics Research and Re-Evaluation Key Laboratory of Sichuan Province, Institute for Advanced Study, Chengdu University, Chengdu, 610106, China.
Xinyi ZhouAntibiotics Research and Re-Evaluation Key Laboratory of Sichuan Province, Institute for Advanced Study, Chengdu University, Chengdu, 610106, China.
Kelei ZhaoAntibiotics Research and Re-Evaluation Key Laboratory of Sichuan Province, Institute for Advanced Study, Chengdu University, Chengdu, 610106, China.
Qianglin ZengAntibiotics Research and Re-Evaluation Key Laboratory of Sichuan Province, Institute for Advanced Study, Chengdu University, Chengdu, 610106, China.
Nan YangKey Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Sichuan Province and Ministry of Education, Southwest Minzu University, Chengdu, 610225, China. yangnan0204@126.com.

Funding

National Natural Science Foundation of China 32200525
6 · The paper itself

Abstract

backgroundTandem repeats (TRs) are major sources of genetic variation and important genetic markers. Their expansions are not only involved in gene expression regulation but also associated with many nervous system diseases and cancers. However, there is a lack of an efficient tandem repeat identification tool for seamless integration with larger bioinformatics programs developed with the popular Python language.

resultsWe introduce pytrf, a Python package for identification of both exact and approximate TRs from genomic sequences. It allows seamless embedding into other programs developed by Python or using in Python interactive environment and Jupyter notebooks. It also provides command line tools for assisting users to find tandem repeats from FASTA/Q files. Compared to other tools, the pytrf shows the highest performance in aspect of running time with comparable peak memory usage.

conclusionsPytrf provides simple interfaces and command line tools to facilitate identification of tandem repeats from genomic sequences. Pytrf can easily be installed from PyPI ( https://pypi.org/project/pytrf ) and the source code is freely available at https://github.com/lmdu/pytrf .

Indexed as

GenomicsSequence Analysis, DNASoftwareTandem Repeat SequencesComputational BiologyHumansProgramming LanguagesGenetic markerGenome analysisMicrosatelliteMinisatelliteTandem repeats

Identifiers

PMID40462000
PMCPMC12135533

What OpenQuestion holds

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LicenceCC BY-NC-ND
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None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.