SynthesisBMC anesthesiology2025
Global prevalence of postoperative hypoxemia among adult and pediatric surgical patients: a systematic review and meta-analysis.
Synthesis in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Perioperative hyperbaric oxygen therapy: mechanisms, evidence, and clinical application.Medical gas research · 2027Review
- Enhancing the evidence for opioid-free anaesthesia in the elderly: a call for methodological clarity.Annals of medicine · 2026Article
- Development and Validation of a Machine Learning-Based Risk Assessment Tool for In-Hospital Mortality in Elderly Patients with Postoperative Hypoxemia Following Non-Cardiac Surgery.Journal of clinical medicine · 2026Article
- Best Evidence Summary of Nursing Management for Perioperative Patients with Hypoxemia.Journal of multidisciplinary healthcare · 2026Review
- Review
- High-Flow Nasal Cannula in Weaning Patients from Mechanical Ventilation in Head and Neck Surgery: Retrospective Study.Life (Basel, Switzerland) · 2025Article
- Risk factors for hypoxemia during pediatric anesthesia: a logistic regression analysis.American journal of translational research · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative hypoxemia refers to a condition where oxygen levels in the tissues or blood drop to insufficient levels following surgery. The aim of this review is to determine the global prevalence of postoperative hypoxemia among adult and pediatric surgical patients through a systematic review and meta-analysis.
methodsWe performed a comprehensive search across multiple databases, including Pubmed, Embase and Scopus. Additionally, search engines such as Google Scholar and Google. The searching mechanism was using medical subject heading terms combining by Boolean operators. The process adhered to the PRISMA guidelines, ensuring a robust method for the review. The review was registered at PROSPERO with registration number CRD42024534623. Risk of bias or quality assessment was done using a standardized critical appraisal instrument. Publication bias was assessed using a funnel plot and Egger's regression test. Pooled prevalence was estimated using random-effects. Subgroup analyses were conducted based on different factors. Additionally, to identify a single study effect sensitivity analysis was conducted.
resultA total of 20 primary studies with 28,948 participants were included. The pooled prevalence of postoperative hypoxemia was 20.62% (95% CI: 17.02-24.22%). Publication bias was detected, with Egger's regression test (p < 0.0001) indicating small-study effects. After imputing three studies, the pooled prevalence decreased from 20.62% (95% CI: 17.02-24.22%) to 16.76% (95% CI: 13.36-20.15%). Subgroup analysis showed the highest prevalence in Africa at 33.81% (95% CI: 25.51-42.1%) and in low-income countries at 33.81% (95% CI: 25.51-42.1%). Among emergency surgical patients, they had the higher prevalence, 21.38% (95% CI: 11.60-31.15%).
conclusionThis meta-analysis showed a pooled prevalence of postoperative hypoxemia was 20.62%, which may be over reported due to publication bias. After data imputation, the revised prevalence was 16.76%. Higher rates are found in Africa and low-income countries, as well as emergency surgical patients.
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