ReviewAAPS PharmSciTech2025
Nanocarrier-based Drug Delivery Systems to Enhance Antimicrobial Photodynamic Therapy in Dental Applications: A Review.
Review in AAPS PharmSciTech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Nano-/Nanobiotechnology-Augmented Pyroptosis in the Treatment of Triple-Negative Breast Cancer: An Updated Review.International journal of nanomedicine · 2026Review
- Effectiveness of Natural Photosensitizers in Antimicrobial Photodynamic Therapy Within Dentistry: A Systematic Review of RCTs.Journal of clinical medicine · 2025Review
- Beyond traditional therapies: a narrative overview of antimicrobial photodynamic therapy in combating bacterial and viral infections.Archives of microbiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial resistance and oral dysbiosis often reduce the efficacy of conventional antimicrobial treatments. In addition, poor permeability and insufficient accumulation of therapeutic agents in biofilms are the main causes of failure in the treatment of oral infections. Antimicrobial photodynamic therapy (PDT) is a versatile therapeutic approach that uses light-activated photosensitizers to fight bacterial infections. When irradiated with light of a specific wavelength, photosensitizers generate reactive oxygen species that selectively damage microbial cells. However, most photosensitizers are poorly soluble in water, which limits their clinical application. Nanotechnology offers a promising solution by incorporating nanocarriers into PDT. Nanocarriers can play a crucial role in improving PDT by overcoming the limitations of conventional photosensitizers. They can encapsulate photosensitizers, protect them from premature degradation, and improve their penetration and delivery to target sites. In this review, different drug delivery systems based on nanocarriers are investigated to improve the efficacy of PDT in dental applications.
Indexed as
Identifiers
40461912What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.