Evidence map›Paper›PMID 40461642›Full record

ArticleOral and maxillofacial surgery2025

Evaluation of the effect of nano-hydroxyapatite/silica gel bone graft and/or hemodialysate paste on the regeneration and nano-mechanical properties of calvarial bone in gammairradiated albino rats.

Noha S Zein, Sara El Moshy, Mohammed Khashaba, Eman M F El-Maghraby, Engy R Rashed, Dalia M Abdel-Hamid

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Article in Oral and maxillofacial surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Noha S ZeinHealth Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt. noha.zein@eaea.sci.eg.
Sara El MoshyOral Biology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.
Mohammed KhashabaOral and Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.
Eman M F El-MaghrabyHealth Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt.
Engy R RashedDrug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt.
Dalia M Abdel-HamidBiomaterials Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEvaluating the effect of synthetic nano-hydroxyapatite/silica gel bone substitute and/or hemodialysate on gamma irradiated bone regeneration and bone nano-mechanical properties in rat model.

methodsSeventy adult male Wistar albino rats (total of 70 defects, 1 defect/rat) were randomly divided into five groups (14 rats/group); 4 irradiated groups; control (Ir-C) without any treatment, NanoBone

resultsScattered thin new bone trabeculae with randomly arranged fine collagen fibrils and extravasated blood were evident in Ir-C group, while thicker new bone trabeculae, well-organized collagen fibers and new blood vessels were observed in all treated groups. Ir-C group showed the lowest significant bone area percent, nano-hardness and indentation modulus values, while Nr-NS group possessed the highest significant percent and values. Ir-C group showed the highest significant indentation modulus to nano-hardness ratio followed by Ir-S group, while the lowest ratios were obtained by the rest of the groups with no significance.

conclusionsThe combination of synthetic nano-hydroxyapatite/silica gel bone substitute and hemodialysate enhanced the quality and quantity of regenerated gamma-irradiated rats' bones. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Bone RegenerationBone SubstitutesBone TransplantationDurapatiteSilica GelSkullAnimalsGamma RaysMaleRandom AllocationRatsRats, WistarBone SubstitutesDurapatiteSilica GelBone graftBone regenerationGamma radiationHemodialysateNano-mechanical properties

Identifiers

PMID40461642
PMCPMC12134040

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.