Evidence map›Paper›PMID 40461630›Full record

ArticleScientific reports2025

Women suffering from overactive bladder syndrome exhibit a higher urethral viral abundance compared to healthy controls: a pilot study.

Marianne Koch, Sara Lado, Barbara Bodner-Adler, Greta Carlin, Cátia Pacífico, Caroline Bauer, Rufus Cartwright, David Seki, Christoph Steininger, Athanasios Makristathis and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marianne KochDepartment of Obstetrics and Gynecology, Medical University of Vienna, Spitalgasse 23, Vienna, 1090, Austria. Marianne.koch@meduniwien.ac.at.
Sara LadoDepartment of Internal Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
Barbara Bodner-AdlerDepartment of Obstetrics and Gynecology, Medical University of Vienna, Spitalgasse 23, Vienna, 1090, Austria.
Greta CarlinDepartment of Obstetrics and Gynecology, Medical University of Vienna, Spitalgasse 23, Vienna, 1090, Austria.
Cátia PacíficoUnit of Food Hygiene and Technology, Institute of Food Safety, Food Technology and Veterinary Public Health, University of Veterinary Medicine Vienna, Vienna, Austria.
Caroline BauerDepartment of Obstetrics and Gynecology, Medical University of Vienna, Spitalgasse 23, Vienna, 1090, Austria.
Rufus CartwrightDepartment of Obstetrics and Gynecology, Chelsea & Westminster NHS Foundation Trust, London, UK.
David SekiDivision of Clinical Microbiology, Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Christoph SteiningerDepartment of Internal Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
Athanasios MakristathisDivision of Clinical Microbiology, Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Wolfgang UmekDepartment of Obstetrics and Gynecology, Medical University of Vienna, Spitalgasse 23, Vienna, 1090, Austria.

Funding

OeNB Jubiläumsfonds 1815
6 · The paper itself

Abstract

The interactions between the human bacterial microbiome and essential bodily functions are well established for organ systems such as the oral cavity, gut, and female reproductive tract. However, the urinary microbiome, particularly its viral component, remains largely unexplored. Emerging evidence suggests that the urinary microbiome may play a significant role in the development of overactive bladder syndrome (OAB). This study aims to fill this knowledge gap by investigating the potential link between the urethral virome and female overactive bladder syndrome, and by aligning these findings with the bacterial microbiome. Prospective pilot study including 15 patients with overactive bladder syndrome and five controls. Current urinary tract infection and antibiotic therapy within the last two months were ruled out and controls were matched to cases by age and body mass index. Urethral swabs (Copan eSwab

Indexed as

UrethraUrinary Bladder, OveractiveVirusesAdultAgedBacteriaCase-Control StudiesFemaleHigh-Throughput Nucleotide SequencingHumansMicrobiotaMiddle AgedPhylogenyPilot ProjectsProspective StudiesVirome

Identifiers

PMID40461630
PMCPMC12134358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.