Evidence map›Paper›PMID 40461484›Full record

ArticleScientific reports2025

Chromosome-scale genome assembly and annotation of two geographically distinct strains of malaria vector Anopheles albimanus.

Dieunel Derilus, Gareth D Weedall, Michael W Vandewege, Dhwani Batra, Mili Sheth, Lori A Rowe, Ananias A Escalante, Audrey Lenhart, Lucy Mackenzie Impoinvil

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dieunel DerilusEntomology Branch, Division of Parasitic Diseases and Malaria, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. qlk5@cdc.gov.
Gareth D WeedallSchool of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK.
Michael W VandewegeDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, 27607, USA.
Dhwani BatraOffice of Advanced Molecular Detection, Division of Infectious Disease Readiness and Innovation, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Mili ShethBiotechnology Core Facility Branch, Division of Core Laboratory Services and Response. Office of Laboratory Safety and Response. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Lori A RoweDepartment of Microbiology, Viral Characterization, Isolation, Production and Sequencing Core, Tulane National Primate Research Center, Tulane University, Covington, LA, USA.
Ananias A EscalanteDepartment of Biology/Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA, USA.
Audrey LenhartEntomology Branch, Division of Parasitic Diseases and Malaria, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Lucy Mackenzie ImpoinvilEntomology Branch, Division of Parasitic Diseases and Malaria, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. ykd8@cdc.gov.

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
NIH HHS P51 OD011104
6 · The paper itself

Abstract

Anopheles albimanus is one of the principal malaria vectors in the Americas and exhibits phenotypic variation across its geographic distribution. High-quality reference genomes from geographically distant populations are essential to deepen our understanding of the biology, evolution, and genetic variation of this important malaria vector. In this study, we applied long-read PacBio and short-read Illumina sequencing technologies to assemble the complete genomes of two reference strains of An. albimanus, Stecla (originating from El Salvador), and Cartagena (originating from Colombia); and investigated the structural features of these genomes, including gene content, transposable elements (TEs), genetic variation, and structural rearrangements. Our hybrid assembly approach generated reference-quality genomes for each strain and recovered ~ 96% of the expected genome size. The genome assemblies of Stecla and Cartagena consisted of 109 and 149 scaffolds, with estimated genome sizes of 167.5 Mbp (N

Indexed as

AnophelesChromosomes, InsectGenome, InsectMalariaMosquito VectorsAnimalsDNA Transposable ElementsGenetic VariationMolecular Sequence AnnotationDNA Transposable ElementsAnopheles albimanusCartagenaHybrid assemblyIllumina SequencingMosquito genomePacBio SequencingStecla

Identifiers

PMID40461484
PMCPMC12134381

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.