Evidence map›Paper›PMID 40461428›Full record

ArticleJournal of veterinary science2025

Safety and efficacy of a

Ji Young Jang, Byung Joon Park, Huiyeon Song, Seungshik Rha, Hyoung Joon Moon, Han Sang Yoo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ji Young JangDepartment of Infectious Disease, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0009-0008-9862-4423
Byung Joon ParkGreen Cross Veterinary Products Co., Ltd., Yongin 17095, Korea.ORCID https://orcid.org/0000-0003-1901-0869
Huiyeon SongGreen Cross Veterinary Products Co., Ltd., Yongin 17095, Korea.ORCID https://orcid.org/0009-0002-5523-5985
Seungshik RhaGreen Cross Veterinary Products Co., Ltd., Yongin 17095, Korea.ORCID https://orcid.org/0009-0005-6009-6141
Hyoung Joon MoonDepartment of Animal Health and Welfare, Semyung University, Jecheon 27136, Korea.ORCID https://orcid.org/0000-0001-6211-8758
Han Sang YooDepartment of Infectious Disease, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea. yoohs@snu.ac.kr.ORCID https://orcid.org/0000-0003-0548-0835

Funding

Research Institute of Green Cross Veterinary ProductsSeoul National University
6 · The paper itself

Abstract

importance

objectiveThis study evaluated the safety and efficacy of

methodsThe immune responses and side effects were assessed after vaccination with OMPs and DNT as subunit vaccine candidates, individually and in combination. The safety evaluations included monitoring the body temperature, weight, and vitality scores, while the efficacy was measured using immunoglobulin quantification, hemagglutination-inhibition (HI) assays, and challenge tests. The vaccine candidates were compared with conventional vaccine formulations.

resultsThe OMP-based vaccine induced a T helper 1-biased immune response, providing robust protection against CONCLUSIONS AND RELEVANCE: OMPs are a promising, cost-effective component for

Indexed as

Bacterial Outer Membrane ProteinsBordetella bronchisepticaVaccines, SubunitAnimalsBordetella InfectionsDog DiseasesDogsFemaleImmunoglobulin GMiceMice, Inbred ICRModels, AnimalTh1 CellsTransglutaminasesTreatment OutcomeVaccine DevelopmentBacterial Outer Membrane Proteinsdermonecrotic toxin, BordetellaImmunoglobulin GTransglutaminasesVaccines, SubunitVirulence Factors, Bordetellabacterial outer membrane proteinsBordetella bronchisepticaSubunit vaccineTH-1 cellsvaccine effectiveness

Identifiers

PMID40461428
PMCPMC12146018

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.