Evidence map›Paper›PMID 40461290›Full record

ArticleZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2025

[Effects of kidney-tonifying Chinese herbs on thymus regene-ration after rapamycin-induced degeneration in mice].

Xunuo Wen, Meiru Zhou, Fengjie Zhang, Yaoying Shu, Jianli Gao

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xunuo WenSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 311499, China. 1827937019@qq.com.
Meiru ZhouSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 311499, China.
Fengjie ZhangSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 311499, China.
Yaoying ShuSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 311499, China.
Jianli GaoSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 311499, China. jianligao@zcmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the effect of a variety of kidney-tonifying Chinese medicines on thymus regeneration after acute degeneration in mice.

methodsForty-eight 8-week-old male BALB/c mice were randomly divided into normal control group, model control group, negative control group, positive control group, the fructus of

resultsRapamycin induced thymic atrophy and significantly reduced limb grip strength in mice (

conclusionsThe tuber onion seed and other kidney-tonifying traditional Chinese medicines can accelerate the regeneration process of mouse thymus after acute degeneration induced by rapamycin in mice, and the tuber onion seed exhibits the most pronounced therapeutic effect.

Indexed as

Drugs, Chinese HerbalRegenerationThymus GlandAnimalsMaleMiceMice, Inbred BALB CSirolimusDrugs, Chinese HerbalSirolimusAnti-agingKidney-tonifying Chinese medicineMiceRegenerationThymusTuber onion seed

Identifiers

PMID40461290
PMCPMC12176542

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.