ArticleBMJ mental health2025
General disease factor: evidence of a unifying dimension across mental and physical illness in children and adolescents.
Article in BMJ mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Neural-genetic-environmental evidence for a disease factor in mental and physical health multimorbidity.Nature communications · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundUnderstanding the relationship between mental and physical health conditions is crucial for developing comprehensive healthcare strategies. The putative existence of a general disease factor (
objectiveTo investigate the presence and characteristics of a general
methodsThis Swedish registry-based cross-sectional study included children and adolescents born between 1996 and 2003 with follow-up until 2013. We extracted data on 25 mental and physical health conditions according to the ICD-10 system. To determine the optimal dimensional structure of these conditions, several competing measurement models were tested, including correlated factors, one factor, various bifactor specifications and bifactor exploratory structural equation modelling (ESEM).
findingsThe study cohort included 776 667 individuals (mean age 13.96 years, IQR=11.96-16.04; 51% male). The bifactor ESEM model, including a general
conclusionsThis study provided evidence for a multidimensional structure of health in children and adolescents, characterised by a general
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