Evidence map›Paper›PMID 40461185›Full record

ArticleOpen heart2025

Asymptomatic carotid artery stenosis and stroke risk in patients undergoing CABG.

Leo Pölzl, Ronja Lohmann, Christian Sutter, Clemens Engler, Michael Graber, Felix Nägele, Jakob Hirsch, Jonas Eder, Maria Ioannou-Nikolaidou, Antonia Lutz and 12 more

Abstract read
In one paragraph

Article in Open heart, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Leo PölzlDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-6552-8899
Ronja LohmannDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Christian SutterDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Clemens EnglerDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Michael GraberDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Felix NägeleDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Jakob HirschDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Jonas EderDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Maria Ioannou-NikolaidouDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Antonia LutzUniversity Hospital of Internal Medicine III, Medical University of Innsbruck, Innsbruck, Austria.
Franziska HübnerUniversity Hospital of Internal Medicine III, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0009-0005-5140-3912
Maria NoflatscherUniversity Hospital of Internal Medicine III, Medical University of Innsbruck, Innsbruck, Austria.
Rudolf KirchmairUniversity Hospital of Internal Medicine III, Medical University of Innsbruck, Innsbruck, Austria.
Elfriede RuttmannDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Sebastian ReinstadlerUniversity Hospital of Internal Medicine III, Medical University of Innsbruck, Innsbruck, Austria.
Michael KnoflachDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Michael GrimmDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Axel BauerUniversity Hospital of Internal Medicine III, Medical University of Innsbruck, Innsbruck, Austria.
Nikolaos BonarosDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-7656-5812
Johannes HolfeldDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
C Gollmann-TepeköylüDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria Can.gt@i-med.ac.at.
Markus TheurlUniversity Hospital of Internal Medicine III, Medical University of Innsbruck, Innsbruck, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePerioperative stroke associated with coronary artery bypass grafting (CABG) is a catastrophic event. Identification of patients at risk and reduction of its incidence remains of high importance. The aim of this study was to analyse the association of different degrees of asymptomatic carotid artery stenosis (CAS) with the perioperative outcome in a consecutive series of CABG patients and to identify predictors for CABG associated ischaemic stroke.

methodsIn total, 2727 patients undergoing isolated CABG procedure at the Medical University of Innsbruck between 2010 and 2020 were included in this study. Sonography data included the severity of carotid stenosis for left and right internal carotid artery individually. The primary outcome was the 30-day stroke and mortality rate, and the secondary outcome was 5-year mortality. A Cox regression model was performed after adjustment for EuroSCORE II.

resultsLeft CAS>50% was present in 177 patients (7%) and right CAS>50% in 197 patients (7.8%). In total, 1.6% (40 patients) of the patients died within 30 days after surgery, and 1.0% (24 patients) experienced a postoperative stroke within 30 days. Patients with a carotid stenosis>90% had a higher 30-day mortality (p<0.001) and higher incidence of postoperative stroke within 30 days (p=0.005). Patients with a history of a prior stroke were at higher risk of experiencing another stroke within 30-days after surgery, with an HR of 6.829 (2.811-16.589) (p<0.001).

conclusionsAsymptomatic CAS>90% and history of stroke are both independent risk factors for perioperative stroke and 30-day mortality.

Indexed as

Carotid StenosisCoronary Artery BypassCoronary Artery DiseasePostoperative ComplicationsStrokeAgedAsymptomatic DiseasesFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsCARDIAC SURGERYCarotid ArteriesCoronary Artery BypassSTROKE

Identifiers

PMID40461185
PMCPMC12142101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.