Observational studyJournal of Korean medical science2025
Non-Linear Relationship Between Alcohol Consumption and Neurological Outcomes in Patients With Out-of-Hospital Cardiac Arrest Presenting to the Emergency Department.
Observational study in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03222999 (Korean Cardiac Arrest Research Consortium), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Korean Cardiac Arrest Research Consortium
Who cites it
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOut-of-hospital cardiac arrest (OHCA) is a major public health issue associated with low survival rates and poor neurological outcomes. Comorbidities and various triggers are associated with OHCA incidence and outcomes. However, the association between alcohol consumption and the neurological prognosis in patients with OHCA remains unknown. Therefore, this study aimed to examine the potential association between the frequency of alcohol consumption and neurological outcomes in patients with OHCA.
methodsThis retrospective observational study used data from the Korean Cardiac Arrest Research Consortium registry, encompassing 62 hospitals in Korea. Patients aged > 18 years who experienced OHCA and were transported by the public emergency medical service system were included. Alcohol consumption was categorized into four groups: never drinkers, light drinkers, moderate drinkers, and heavy drinkers. The primary outcome measured was a favorable neurological outcome at hospital discharge (cerebral performance category score 1 or 2).
resultsAmong the 6,671 enrolled patients, 14.7% had favorable neurological outcomes. The odd ratio of achieving a good neurologic outcome was reduced by 0.597 (95% confidence interval [CI], 0.444-0.802;
conclusionThis study revealed a nonlinear association between the frequency of alcohol consumption and neurological prognosis in patients with OHCA. Therefore, future studies should focus on investigating the mechanism underlying the potential brain-protective effects of alcohol to further understand its impact on neurological recovery following OHCA.
trial registrationClinicalTrials.gov Identifier: NCT03222999.
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