Evidence map›Paper›PMID 40460986›Full record

ArticleAnalytical biochemistry2025

Recombinase polymerase amplification for single nucleotide polymorphism-specific detection of β

Mehnaz Urbee Jahangir, Megan M Chang, Alexis Wilkinson, Zoha Wazir, Venée N Tubman, Gladstone E Airewele, Rebecca Richards-Kortum

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mehnaz Urbee JahangirDepartment of Bioengineering, Rice University, Houston, TX, USA.
Megan M ChangDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
Alexis WilkinsonDepartment of Bioengineering, Rice University, Houston, TX, USA.
Zoha WazirDepartment of Bioengineering, Rice University, Houston, TX, USA.
Venée N TubmanTexas Children's Cancer and Hematology Centers, Houston, TX, USA; Baylor College of Medicine, Houston, TX, USA.
Gladstone E AireweleTexas Children's Cancer and Hematology Centers, Houston, TX, USA; Baylor College of Medicine, Houston, TX, USA.
Rebecca Richards-KortumDepartment of Bioengineering, Rice University, Houston, TX, USA. Electronic address: rkortum@rice.edu.

Funding

A Sample-to-Answer Point-of-Care Diagnostic for Recently Transfused Sickle Cell Anemia Patients in Low Resource SettingsR01HL166413 · NHLBI · RICE UNIVERSITY · PI Rebecca R. Richards-Kortum · 2023 to 2026
$2.4M
Characterization of B Lymphocyte Deficiency in Pediatric Sickle Cell DiseaseK23HL148548 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI TUBMAN, VENEE N · 2020 to 2024
$816k
NHLBI NIH HHS K23 HL148548NHLBI NIH HHS R01 HL166413
6 · The paper itself

Abstract

Sickle cell disease (SCD) comprises a group of inherited blood disorders caused by point mutations in the β-globin gene. SCD is characterized by at least one β

Indexed as

Anemia, Sickle Cellbeta-GlobinsNucleic Acid Amplification TechniquesPolymorphism, Single NucleotideRecombinasesAllelesHumansbeta-GlobinsRecombinasesAmplification refractory mutation systemLocked nucleic acidRecombinase polymerase amplificationSingle nucleotide polymorphism

Identifiers

PMID40460986
PMCPMC13135376

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.