ArticleCell reports. Medicine2025
Visceral fat lipolysis by pancreatic lipases worsens heart failure.
Article in Cell reports. Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Review
- Article
- Molecular Mechanisms and Therapeutic Potential of Baicalein in Acute Pancreatitis: A Comprehensive Review.Biomolecules · 2026Review
- Identification and preliminary clinical validation of type 2 diabetes signature genes through machine learning analysis of scRNA-seq data.Frontiers in medicine · 2026Article
- METS-VF and METS-IR as predictors of acute myocardial infarction in U.S. adults: Evidence from NHANES 2005 to 2018.Medicine · 2025Article
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Authors and funding
14 authors.
Funding
Abstract
Heart failure can be worse when associated with obesity, elevated serum pancreatic enzymes, elevated non-esterified fatty acids (NEFAs), or acute pancreatitis (AP). To understand this, here we study doxorubicin-induced heart failure, experimental AP, or pancreatic lipase-induced visceral fat necrosis in lean, genetically obese (ob/ob), or dual ob/ob pancreatic triglyceride lipase (PNLIP)-knockout mice. NEFA generation and resulting cardiac injury are measured. We note that ob/ob mice develop fat necrosis containing PNLIP and phospholipase A
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