Evidence map›Paper›PMID 40460137›Full record

ArticlePloS one2025

Cost-effectiveness analysis of a postoperative 48-hour care bundle for high-risk patients undergoing abdominal surgery.

Cleiton Pando, Ana Paula Etges, Miriam Z Marcolino, Ricardo B Cardoso, Adriene Stahlschmidt, Carise A Polanczyk, Luciana C Stefani

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cleiton PandoPrograma de Pós-Graduação em Ciências Médicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
Ana Paula EtgesDepartamento de Epidemiologia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
Miriam Z MarcolinoNational Institute of Science and Technology for Health Technology Assessment, INCT/IATS, Porto Alegre, Brazil.
Ricardo B CardosoNational Institute of Science and Technology for Health Technology Assessment, INCT/IATS, Porto Alegre, Brazil.
Adriene StahlschmidtServiço de Anestesia e Medicina Perioperatória, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil.ORCID 0000-0002-1136-7348
Carise A PolanczykDepartamento de Epidemiologia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
Luciana C StefaniPrograma de Pós-Graduação em Ciências Médicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.ORCID 0000-0002-3038-3108

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnhancing surgical care pathways, including scaling-up care after surgery, seeks to deliver better patient-centered care and improve outcomes. However, the value associated with these pathways need to be investigated.

methodsWe analyzed the potential increase in efficiency of a new care pathway, a postoperative 48-hour care bundle designed to enhance care for high-risk patients undergoing major abdominal surgery, based on micro-costing and cost-effectiveness analyses. Data from a prospective cohort of patients who underwent a high-risk surgical bundle were compared with those who received the standard care regimen. The bundle included standardized risk communication using the ex-care model, implementing a high-risk patient discharge checklist from the recovery room to the ward, ensuring prompt nursing admission to the ward, increasing the frequency of vital sign monitoring in the surgical ward, conducting troponin measurements, and providing rapid access to medical support when needed. Costs were calculated individually throughout the postoperative period until discharge following the time-driven activity-based costing method. One-year survival rates were evaluated using Kaplan-Meier survival curves. A cost-effectiveness analysis was conducted in terms of life-year gain (LYG) and incremental cost-effectiveness ratio (ICER).

resultsData from 130 and 188 patients in the bundled and non-bundled groups, respectively, were evaluated. The mean cost per patient of the high-risk surgical bundle was US$2114.63 while for the conventional care group it was US$1447.86. The Kaplan-Meier curve for one-year mortality showed that the groups differed significantly (p =  0.002). According to the model, the new care strategy incremented 0.12 life-year gained at an incremental cost of $150.12. The projected incremental cost-effectiveness ratio for one year of life was $1217.66.

conclusionOur results suggest that implementing a high-risk surgical bundle can enhance healthcare delivery efficiency, making it a valuable and cost-effective strategy for high-level testing to create a more sustainable healthcare system.

Indexed as

AbdomenCost-Benefit AnalysisPatient Care BundlesPostoperative CareAgedCost-Effectiveness AnalysisFemaleHumansMaleMiddle AgedProspective Studies

Identifiers

PMID40460137
PMCPMC12132966

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.