Evidence map›Paper›PMID 40460120›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

John M Webb, Fayal Abderemane-Ali, Liza Ashbrook, Mingyang Ma, Neha Nibber, Xianlin Zou, Maya Yamazaki, Elizabeth Wohler, Nara Sobreira, Daniel L Minor and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Emerging genetics of sleep and circadian disorders.Current opinion in pediatrics · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

John M WebbDepartment of Neurology, University of California San Francisco, San Francisco, CA 94143.
Fayal Abderemane-AliCardiovascular Research Institute, University of California, San Francisco, CA 94143.
Liza AshbrookDepartment of Neurology, University of California San Francisco, San Francisco, CA 94143.
Mingyang MaDepartment of Neurology, University of California San Francisco, San Francisco, CA 94143.
Neha NibberDepartment of Neurology, University of California San Francisco, San Francisco, CA 94143.
Xianlin ZouDepartment of Neurology, University of California San Francisco, San Francisco, CA 94143.
Maya YamazakiDepartment of Neurology, University of California San Francisco, San Francisco, CA 94143.
Elizabeth WohlerMcKusick-Nathans Department of Genetic Medicine, Johns Hopkins Medicine, Baltimore, MD 21205.
Nara SobreiraMcKusick-Nathans Department of Genetic Medicine, Johns Hopkins Medicine, Baltimore, MD 21205.
Daniel L MinorKavli Institute for Fundamental Neuroscience, University of California San Francisco, San Francisco, CA 94143.ORCID 0000-0002-5998-4214
Ying-Hui FuDepartment of Neurology, University of California San Francisco, San Francisco, CA 94143.
Louis J PtáčekDepartment of Neurology, University of California San Francisco, San Francisco, CA 94143.

Funding

Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VAISSE, CHRISTIAN · 2003 to 2019
$21.8M
Illuminating Druggable Dark MatterU24DK116214 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAN, LILY Y, MCMANUS, MICHAEL T · 2017 to 2022
$12.9M
Structure and function of voltage-gated calcium channelsR01HL080050 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DANIEL L MINOR · 2005 to 2026
$9.8M
Probing genetics and biology of human sleep homeostasisR01NS117929 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PTACEK, LOUIS J. · 2021 to 2025
$3.3M
Probing genetics and biology of human circadian functionR01NS099333 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PTACEK, LOUIS J. · 2017 to 2021
$2.9M
American Heart Association (AHA) an American Heart Association postdoctoral fellowshipHHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS099333HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS117929NHLBI NIH HHS R01 HL080050NIDDK NIH HHS P30 DK063720NIDDK NIH HHS U24 DK116214NINDS NIH HHS R01 NS099333NINDS NIH HHS R01 NS117929UCSF | Diabetes Center, University of California, San Francisco (UCSF Diabetes Center) U24DK116214 for Understudied ion channels
6 · The paper itself

Abstract

Familial advanced sleep phase (FASP) is a heritable human sleep trait characterized by early sleep onset and offset times. We have identified five variants in five different families in the human voltage-gated calcium channel subunit alpha1 D (

Indexed as

Calcium Channels, L-TypeCircadian RhythmSleepSleep Disorders, Circadian RhythmAnimalsFemaleHumansMaleMicePedigreeCalcium Channels, L-Typecircadian rhythmsFASPhuman genetics

Identifiers

PMID40460120
PMCPMC12167976

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.