ArticleChemSusChem2025
Cutinases for Biocatalytic Polycarbonate Hydrolysis: Empowering Circular Economy.
Article in ChemSusChem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Defined Nylon Oligomers Enable Mechanistic Insight Into Enzymatic Polyamide Depolymerization.ChemSusChem · 2026Article
- Depolymerization and Reuse of Polycarbonates: Emerging Classes, Mechanisms and Challenges.Angewandte Chemie (International ed. in English) · 2026Review
- Directed Evolution of an Efficient Polycarbonate Depolymerase With Exceptional Operational Stability.Angewandte Chemie (International ed. in English) · 2026Article
- Microbial plastic degradation: enzymes, pathways, challenges, and perspectives.Microbiology and molecular biology reviews : MMBR · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
While synthetic polymers are indispensable for the sustainable transformation of society, the increasing production needs to be combined with adequate recycling strategies. As conventional recycling processes often result in quality losses or are complicated by the presence of additives and other polymers, there is a high need for the development of new technologies. This study presents a first efficient approach to enzymatically recycle polycarbonate (PC), a high-performance polymer. Through an extensive enzyme screening, 9 cutinases are found to exhibit hydrolytic activity toward PC in aqueous buffer enabling the recovery of bisphenol A (BPA) as a valuable monomer under mild reaction conditions. Notably, the enzymes ThcCut1-ACCG and LCC-ICCG demonstrate excellent performance by achieving conversions of 20-40% under optimized reaction conditions. Impressively, full conversion of PC can be achieved by supplementing dimethyl sulfoxide (DMSO; 30% v/v). These findings represent an excellent foundation to develop sustainable PC recycling processes for the circular economy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.