Evidence map›Paper›PMID 40459947›Full record

ReviewClinical journal of the American Society of Nephrology : CJASN2026

Dietary Protein Intake in CKD: Quantity and Quality.

Denis Fouque, Denise Mafra, Vincenzo Bellizzi

Abstract readReview
In one paragraph

Review in Clinical journal of the American Society of Nephrology : CJASN, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Denis FouqueDepartment of Nephrology, Hospices Civils de Lyon, University Claude Bernard Lyon 1, Pierre-Bénite, France.ORCID 0000-0002-9707-7199
Denise MafraGraduate Program in Nutrition Sciences, Fluminense Federal University (UFF), Rio de Janeiro, Brazil.ORCID 0000-0001-6752-6056
Vincenzo BellizziDivision of Nephrology and Dialysis, Sant'Anna e San Sebastiano Hospital, Caserta, Italy.ORCID 0000-0001-9374-0152

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An intensive management, including nutritional interventions, is crucial for reducing mortality and improving outcomes in patients with CKD. Dietary protein reduction has been a key strategy in CKD management since the 1930s, when specialized diets were used to treat uremic symptoms. Research has shown that excessive protein intake exacerbates kidney damage, while a controlled protein intake reduces metabolic toxins and their harmful effects. Evidence indicates that animal proteins contribute to the production of uremic toxins; in contrast, a plant-based diet offers numerous benefits as long as the sources are combined to ensure a complete essential amino acid profile. This review explores the optimal protein intake for patients with CKD, focusing on the quantity and quality of dietary proteins and the optimal way to ensure a sustained compliance over time.

Indexed as

Dietary ProteinsDiet, Protein-RestrictedRenal Insufficiency, ChronicDiet, VegetarianHumansPlant Proteins, DietaryDietary ProteinsPlant Proteins, DietaryCKD nondialysismalnutritionnutrition

Identifiers

PMID40459947
PMCPMC12959747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.