ArticleMolecular biology reports2025
Characterization of multidrug-resistant Escherichia coli isolated from clinical (UPEC) and environmental samples.
Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Prevalence and molecular characterization of ESBL-producing Enterobacterales in clinical samples from the Boucle du Mouhoun region in Burkina Faso.BMC infectious diseases · 2026Article
- Cocktail of genetically diverse lytic phages reduces uropathogenic Escherichia coli colonization in mouse urinary tract.Scientific reports · 2026Article
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Authors and funding
6 authors.
Funding
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Abstract
backgroundEscherichia coli (E. coli) is a significant cause of urinary tract infections (UTIs). METHODS AND
resultsIn this study, a total of 1,040 samples comprising treated Wastewater (57), Nile River water (400), and urine from suspected UTI patients (583) were collected between September 2019 and March 2020. E. coli was prevalent in Wastewater (84.2%), river water (63.3%), and 33.5% of urine samples. All extended-spectrum β-lactamase-producing E. coli (ESBLEC) isolates were fully resistant to penicillins and cephems. Multidrug resistance (MDR) was found in 70.7% of Wastewater and 87% of river isolates, with notable resistance to ampicillin/sulbactam, sulfamethoxazole-trimethoprim, and ciprofloxacin. Clinical isolates showed 62.5% MDR but remained susceptible primarily to ciprofloxacin and entirely to meropenem. Phylogenetic analysis revealed diverse chlorine-tolerant Uropathogenic E. coli strains, suggesting environmental spread.
conclusionThese results highlight wastewater treatment plants as key reservoirs of MDR E. coli and stress the need for better surveillance and control in Egypt.
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