Evidence map›Paper›PMID 40459788›Full record

ArticleDiscover oncology2025

Bibliometric analysis of MXRA7 gene research trajectory: trends and insights (2015-2024).

Huihui Zhang, Ying Shen, Peijian Bai, Xiaorui Wu, Ping Li, Ting Wang

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Huihui Zhang *Oncology Department of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, 230001, China.
Ying Shen *National Clinical Research Center for Hematologic Disease, Institute of Blood and Marrow Transplantation of Soochow University, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.
Peijian BaiOncology Department of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, 230001, China.
Xiaorui WuOncology Department of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, 230001, China.
Ping LiOncology Department of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, 230001, China. liping1964@ahmu.edu.cn.
Ting WangOncology Department of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, 230001, China. wangting921204@163.com.

Funding

National Natural Science Foundation of China No. 82300281
6 · The paper itself

Abstract

backgroundMatrix remodeling-associated 7 (MXRA7) plays a key role in physiological and pathological processes involving the extracellular matrix (ECM) and tissue remodeling. Recent studies have highlighted its functions in tissue injury, immune response, and cellular differentiation, yet no bibliometric studies have systematically mapped MXRA7 research. This study evaluates global MXRA7 research from 2015 to 2024 to identify current trends and future directions.

methodsA comprehensive bibliometric analysis was conducted using the Web of Science Core Collection. We examined publication trends, geographical contributions, influential authors, and high-impact journals, identifying research hotspots and emerging trends with advanced bibliometric tools.

resultsAnalysis of 553 English-language publications showed that MXRA7 research has progressed significantly after 2017, showing a general upward trend accompanied by short-term fluctuations. The United States leads, followed by China and the United Kingdom. Key studies appear in high-impact journals like PLOS ONE, and influential authors such as Frangogiannis NG have propelled the field. Keywords including "inflammation", "extracellular matrix", "matrix metalloproteinases" and "angiogenesis" underscore MXRA7's roles in immune responses, tissue repair, and fibrosis.

conclusionThis analysis shows significant growth in MXRA7 research, especially in inflammation, ECM remodeling, and tissue regeneration. Future work should explore MXRA7's molecular mechanisms in immune diseases, fibrosis, and cancer, advancing its potential as a therapeutic target.

Indexed as

BibliometricsExtracellular matrix remodelingMatrix remodeling-associated 7

Identifiers

PMID40459788
PMCPMC12134252

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.