ReviewJapanese journal of radiology2025
Current perspectives and emerging trends in iodine-125 seed implantation: a comprehensive bibliometric analysis.
Review in Japanese journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Gut Microbiota Dysbiosis MediatesImmunity, inflammation and disease · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIodine-125 (125-I) seed implantation is a widely used brachytherapy technique for treating various solid tumors. This study aims to provide a bibliometric analysis of the research trends, key contributors, and emerging hotspots in this field. MATERIALS AND
methodsA comprehensive search was conducted using the Web of Science Core Collection, covering publications from January, 1960 to August 20, 2024. Bibliometric analysis was performed with VOSviewer, CiteSpace, and the R package "bibliometrix" to examine trends in publications, countries, institutions, journals, authors, and keywords.
resultsThe analysis included 2212 publications, showing a steady increase in research output, with USA, China, and Japan leading in publication volume. The University of California System and Keio University were the most productive institutions. Brachytherapy and the International Journal of Radiation Oncology, Biology, and Physics emerged as the most influential journals in this field. Yorozu Atsunori and Wang Junjie were identified as key authors. Keyword co-occurrence analysis highlighted "cancer," "brachytherapy," and "radiotherapy" as core themes. Keyword burst analysis revealed evolving research hotspots, such as "hepatocellular carcinoma," "efficacy," "safety," and "transarterial chemoembolization," emphasizing concerns about long-term outcomes, safety, and treatment strategies for 125-I implantation therapy across multiple cancers.
conclusionThis bibliometric analysis underscores that research on 125-I seed implantation is primarily focused on optimizing dosimetry, improving implantation techniques, and addressing long-term outcomes and safety. The findings emphasize the need for standardized treatment protocols to ensure consistent and effective clinical practice.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.