Evidence map›Paper›PMID 40459647›Full record

ArticleLa Radiologia medica2025

ADC measurement in whole-body MRI for multiple myeloma: a three b-values vs. two b-values DWI comparison.

Marta Zerunian, Benedetta Masci, Dominga Pugliese, Stefano Nardacci, Michela Polici, Francesco Pucciarelli, Domenico De Santis, Damiano Caruso, Giacinto La Verde, Andrea Laghi

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in La Radiologia medica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marta ZerunianRadiology Unit-Department of Surgical-Medical Sciences and Translational Medicine, Sapienza University of Rome-Sant'Andrea University Hospital, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Benedetta MasciRadiology Unit-Department of Surgical-Medical Sciences and Translational Medicine, Sapienza University of Rome-Sant'Andrea University Hospital, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Dominga PuglieseRadiology Unit-Department of Surgical-Medical Sciences and Translational Medicine, Sapienza University of Rome-Sant'Andrea University Hospital, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Stefano NardacciRadiology Unit-Department of Surgical-Medical Sciences and Translational Medicine, Sapienza University of Rome-Sant'Andrea University Hospital, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Michela PoliciRadiology Unit-Department of Surgical-Medical Sciences and Translational Medicine, Sapienza University of Rome-Sant'Andrea University Hospital, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Francesco PucciarelliRadiology Unit-Department of Surgical-Medical Sciences and Translational Medicine, Sapienza University of Rome-Sant'Andrea University Hospital, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Domenico De SantisRadiology Unit-Department of Surgical-Medical Sciences and Translational Medicine, Sapienza University of Rome-Sant'Andrea University Hospital, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Damiano CarusoRadiology Unit-Department of Surgical-Medical Sciences and Translational Medicine, Sapienza University of Rome-Sant'Andrea University Hospital, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Giacinto La VerdeHematology Unit, Department of Clinical and Molecular Medicine, Sapienza University of Rome-Sant'Andrea University Hospital, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Andrea LaghiRadiology Unit-Department of Surgical-Medical Sciences and Translational Medicine, Sapienza University of Rome-Sant'Andrea University Hospital, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy. andrea.laghi@uniroma1.it.ORCID http://orcid.org/0000-0002-3091-7819

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare apparent diffusion coefficient (ADC) values in whole-body MRI (WB-MRI) reconstructed from diffusion-weighted imaging (DWI) with three b-values (50-500-1000 s/mm MATERIALS AND

methodsPatients with multiple myeloma who underwent 1.5 T WB-MRI were retrospectively included. Exclusion criteria were severe motion artifacts. Examinations included axial DWI with three b-values (50-500-1000 s/mm

resultsFifty-five patients (25 females, 29-83 yo) were retrospectively included; 305 bone lesions and 303 healthy bone segments were assessed. Objective analysis showed different ADC values between bone lesions' in ADC3b and ADC2b (965.3 ± 216.7 µm

conclusionADC2b is comparable with ADC3b except for borderline values (650-750 µm

Indexed as

Diffusion Magnetic Resonance ImagingImage Interpretation, Computer-AssistedMultiple MyelomaWhole Body ImagingAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedReference ValuesRetrospective StudiesSensitivity and SpecificityADCMRI protocolMultiple myelomaQuantitative assessmentWhole-body MRI

Identifiers

PMID40459647

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