ArticleBalkan medical journal2025
Triglyceride-Glucose Index Predicts Major Adverse Cardiovascular and Cerebrovascular Events in Non-Diabetic Individuals
Article in Balkan medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Beyond Traditional Risk Factors: The MAINER Approach to Atherosclerotic Cardiovascular Disease.Balkan medical journal · 2026Article
- Metabolic status modifies the predictive value of the C-reactive protein-triglyceride-glucose Index-waist-to-height ratio for major adverse cardiovascular and cerebrovascular events: a prospective cohort study from the China Health and Retirement Longitudinal Study (CHARLS).Cardiovascular diabetology · 2026Article
- Prognostic value of the CRP-TyG index for in-hospital and 1-year mortality in patients with decompensated heart failure.BMC cardiovascular disorders · 2026Article
- Triglyceride glucose index in patients with acute coronary syndrome undergoing percutaneous coronary intervention predicts cardiovascular events: a cohort study.Cardiovascular diabetology · 2025Observational
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Authors and funding
9 authors.
Funding
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Abstract
Background: The association between the triglyceride-glucose (TyG) index and the occurrence of major adverse cardiovascular and cerebrovascular events (MACCEs) in individuals without diabetes has not been clearly established. Aims: To investigate the potential of the TyG index to predict MACCEs in a non-diabetic population. Study Design: Prospective cohort study. Methods: This study analyzed data from 88,946 participants without diabetes, who were divided into four groups based on their TyG index values. The primary outcome was the occurrence of MACCEs, defined as myocardial infarction (MI) or stroke. Multivariable Cox proportional hazards regression models were used to assess the association between the TyG index and MACCEs. Results: Participants in the higher TyG index quartiles exhibited a greater risk of MACCEs. Moreover, a significant interaction between the TyG index and sex was identified, with a stronger association observed in women than in men. A significant interaction was also found between the TyG index and age in relation to MI risk, indicating a stronger associations in individuals younger than 60 compared to those aged 60 or older. Conclusion: The TyG index may serve as a useful prognostic marker for MACCEs among individuals without diabetes.
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