Evidence map›Paper›PMID 40459365›Full record

ArticleJournal of veterinary internal medicine

Retrospective Evaluation of Transcatheter Edge-To-Edge Mitral Valve Repair in Dogs With Myxomatous Mitral Valve Disease.

Jeong-Min Lee, Kyoung-A Youp, Sun-Tae Lee, Ah-Ra Lee, Young-Wook Cho, Youn-Seo Jung, Jiwoong Her, Seung-Keun Lee

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jeong-Min LeeKorea Animal Medical Center, Cheongju, South Korea.ORCID https://orcid.org/0000-0003-2920-7171
Kyoung-A YoupKorea Animal Medical Center, Cheongju, South Korea.ORCID https://orcid.org/0009-0007-5176-8975
Sun-Tae LeeKorea Animal Medical Center, Cheongju, South Korea.ORCID https://orcid.org/0009-0009-9304-8858
Ah-Ra LeeKorea Animal Medical Center, Cheongju, South Korea.ORCID https://orcid.org/0009-0001-0465-3688
Young-Wook ChoKorea Animal Medical Center, Cheongju, South Korea.ORCID https://orcid.org/0009-0006-4055-8158
Youn-Seo JungKorea Animal Medical Center, Cheongju, South Korea.ORCID https://orcid.org/0000-0002-2849-0107
Jiwoong HerCollege of Veterinary Medicine, North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0003-3150-591X
Seung-Keun LeeKorea Animal Medical Center, Cheongju, South Korea.ORCID https://orcid.org/0009-0000-1557-7206

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter edge-to-edge repair (TEER) is an emerging minimally invasive mitral valve repair treatment for dogs with myxomatous mitral valve disease (MMVD), but reports on its outcomes are limited.

objectiveDescribe the clinical characteristics and complications in dogs with MMVD undergoing TEER. ANIMALS: Twenty client-owned dogs with MMVD stages B2, C, and D.

methodsRetrospective case series. Cases were identified by review of hospital medical records between September 2023 and September 2024.

resultsTwenty dogs underwent TEER; of these, 13 (65%) survived. Seven dogs died within 9 days because of mitral leaflet tear or single-leaflet device attachment (4/7 dogs, 57.1%), tracheal collapse (1/7 dogs, 14.3%), presumed post-procedure neurologic deficit with a history of hydrocephalus (1/7 dogs, 14.3%), and presumed cardiogenic shock (1/7 dogs, 14.3%). Significant reductions in vertebral heart score (11.6 [9.6-13.1] vs. 11.0 [8.3-11.9] vertebrae; p < 0.01), vertebral left atrial size (2.90 [2.1-3.6] vs. 2.60 [2.0-3.3] vertebrae; p < 0.01), left atrium-to-aortic root ratio (2.09 [1.5-2.5] vs. 1.69 [1.3-2.2]; p < 0.05), left ventricular end-diastolic diameter normalized for body weight (2.1 [1.5-2.3] vs. 1.76 [1.4-2.2]; p < 0.05), regurgitant fraction (77.83 [73.2-83.0] vs. 55.38 [20.5-73.6] %; p < 0.05), and regurgitant volume (3.96 [2.1-6.2] vs. 1.25 [0.4-3.5] ml/kg; p < 0.05) were observed 3 months after TEER. CONCLUSIONS AND CLINICAL IMPORTANCE: Transcatheter edge-to-edge repair resulted in a significant reduction in left atrium and ventricle size and should be further investigated as a potential treatment option for dogs with MMVD.

Indexed as

Dog DiseasesMitral ValveMitral Valve InsufficiencyAnimalsDogsFemaleMaleRetrospective StudiesTreatment Outcomecaninemitral valve repairmyxomatous mitral valve diseasetranscatheter edge‐to‐edge repair

Identifiers

PMID40459365
PMCPMC12131550

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.