Evidence map›Paper›PMID 40459299›Full record

ReviewJournal of bacteriology2025

Bacterial ribosome heterogeneity facilitates rapid response to stress.

Yi-Lin Shen, Lei Xu, Ying Zhou, Bang-Ce Ye

Abstract readReview
In one paragraph

Review in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yi-Lin ShenLaboratory of Biosystems and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.ORCID 0000-0002-7078-028X
Lei XuLaboratory of Biosystems and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.ORCID 0009-0003-1296-3138
Ying ZhouLaboratory of Biosystems and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.ORCID 0000-0001-9241-1293
Bang-Ce YeLaboratory of Biosystems and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.ORCID 0000-0002-5555-5359

Funding

China Postdoctoral Science Foundation 2023M741176National Key Research and Development Program of China 2023YFF1204500National Key Research and Development Program of China 2024YFA0917100
6 · The paper itself

Abstract

Bacteria live under constant pressure from external signals, necessitating a rapid capacity to reprogram their metabolism. The ribosome, once considered a uniform and static entity, is now recognized for its compositional heterogeneity. Despite its prevalence, the role of this heterogeneity in regulating bacterial translation remains incompletely understood. This review explores how ribosomal heterogeneity may serve as a conserved mechanism for fine-tuning gene expression, enabling swift adjustments to environmental stress. We present recent findings on the regulatory potential of ribosome heterogeneity and its broader implications for bacterial adaptation, pathogenesis, and the development of novel antimicrobial strategies.

Indexed as

BacteriaGene Expression Regulation, BacterialRibosomesStress, PhysiologicalProtein Biosynthesispost-translational modificationrapid responseribosome heterogeneity

Identifiers

PMID40459299
PMCPMC12186496

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.