Evidence map›Paper›PMID 40459240›Full record

ArticleThe Journal of infectious diseases2025

Differentiating Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Responses Between Infection and Vaccination: Challenges for Epidemiological Research.

Sunav N Nayagam, William Coote, Matthew T C Carroll, Zheng Quan Toh, Paul V Licciardi, Michael J Abramson, Karen Walker-Bone, Tyler J Lane

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sunav N NayagamSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0009-0005-3283-9032
William CooteMonash Rural Health Churchill, Monash University, Churchill, Victoria, Australia.
Matthew T C CarrollMonash Rural Health Churchill, Monash University, Churchill, Victoria, Australia.ORCID 0000-0002-6396-8364
Zheng Quan TohInfection, Immunity and Global Health Theme, Murdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID 0000-0002-0282-5837
Paul V LicciardiInfection, Immunity and Global Health Theme, Murdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID 0000-0001-6086-6285
Michael J AbramsonSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-9954-0538
Karen Walker-BoneSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-5992-1459
Tyler J LaneSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0001-6089-1827

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some common coronavirus disease 2019 (COVID-19) vaccines elicit antibody responses that most serological tests are unable to differentiate from an infection response. This presents a challenge for COVID-19 epidemiology and serosurveys. In this perspective, we examine the potential scale of this problem.

Indexed as

Antibodies, ViralCOVID-19COVID-19 VaccinesSARS-CoV-2Antibody FormationHumansVaccinationAntibodies, ViralCOVID-19 VaccinesantibodiesCOVID-19epidemiologyserologyvaccines

Identifiers

PMID40459240
PMCPMC12308668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.