Evidence map›Paper›PMID 40459120›Full record

ArticleThe Journal of physiology2026

Understanding CPVT pathogenic mechanisms based on mutation location within RyR2: towards personalized medicine?

Jean-Pierre Benitah, Esther Zorio, Ana María Gómez

Abstract read
In one paragraph

Article in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Ca2+ signalling in cardiac muscle: the importance of balances.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jean-Pierre BenitahInserm, UMR-S1180 'Signalling and Cardiovascular Pathophysiology', Université Paris-Saclay, Orsay, France.ORCID https://orcid.org/0000-0002-9866-9081
Esther ZorioInherited Cardiac Diseases Unit, Cardiology Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain.ORCID https://orcid.org/0000-0003-3608-4210
Ana María GómezInserm, UMR-S1180 'Signalling and Cardiovascular Pathophysiology', Université Paris-Saclay, Orsay, France.ORCID https://orcid.org/0000-0003-0009-2884

Funding

Agence Nationale de la Recherche (ANR) ANR-19-CE14-0031-01Agence Nationale de la Recherche (ANR) ANR-23-CE14-0009-02Agence Nationale de la Recherche (ANR) ANR-24-CE14-2131-01
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiac sudden deathCPVTryanodine receptor

Identifiers

PMID40459120
PMCPMC13480994

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.