Evidence map›Paper›PMID 40458824›Full record

ArticleFrontiers in nutrition2025

Therapeutic efficacy of fecal microbiota transplantation in severe food intolerance: a case report.

Yanhui Huang, Jiayuan Huang, Yuange Li, Tianyu Xu, Guoqiao Quan, Peihao Xu, Xiaoya Yang, Zhou Liu, Wenrui Xie

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yanhui Huang *Department of Gastroenterology, Research Center for Engineering Techniques of Microbiota-Targeted Therapies of Guangdong, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Jiayuan Huang *Department of Gastroenterology, Research Center for Engineering Techniques of Microbiota-Targeted Therapies of Guangdong, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Yuange LiDepartment of Gastroenterology, Research Center for Engineering Techniques of Microbiota-Targeted Therapies of Guangdong, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Tianyu XuDepartment of Gastroenterology, Research Center for Engineering Techniques of Microbiota-Targeted Therapies of Guangdong, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Guoqiao QuanDepartment of Gastroenterology, Research Center for Engineering Techniques of Microbiota-Targeted Therapies of Guangdong, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Peihao XuDepartment of Gastroenterology, Research Center for Engineering Techniques of Microbiota-Targeted Therapies of Guangdong, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Xiaoya YangDepartment of Physiology, Guangzhou Health Science College, Guangzhou, China.
Zhou LiuDepartment of Neurology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Wenrui XieDepartment of Gastroenterology, Research Center for Engineering Techniques of Microbiota-Targeted Therapies of Guangdong, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report presents the first documented application of fecal microbiota transplantation (FMT) for the management of extensive multi-food intolerance involving 52 specific foods in a pediatric patient with autism spectrum disorder (ASD). A 7 years-old autistic child was diagnosed with food intolerance to 52 items, presenting with generalized rashes, diarrhea, and malnutrition (BMI of 12.9) upon exposure or ingestion of the implicated foods. The child received oral fecal microbiota capsule treatment, with a daily dose of nine capsules (a total of 120 capsules per course) for two consecutive treatment courses. The rashes resolved, the child regained tolerance to previously intolerable foods, nutritional status improved, and stool consistency normalized. This case suggests that FMT may hold therapeutic potential for managing food intolerance in autistic patients.

Indexed as

autism spectrum disorderfecal microbiota transplantationfood intolerancegastrointestinal symptomsgut microbiota

Identifiers

PMID40458824
PMCPMC12127135

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.