ReviewFrontiers in pharmacology2025
Plant-based secondary metabolites as natural remedies: a comprehensive review on terpenes and their therapeutic applications.
Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Terpesomes as Advanced Nanocarriers for Enhanced Drug Delivery: Formulation Strategies, Mechanistic Insights, and Therapeutic Applications.AAPS PharmSciTech · 2026Review
- Phytochemistry and Pharmacological Potential of the GenusPharmaceuticals (Basel, Switzerland) · 2026Review
- Dietary Terpenoids in Advancing Biofilm-Mediated Cancer Prevention: Antibiofilm Cascade, Molecular Crosstalk, and Nano-Facilitated Functional Delivery.Cell biochemistry and function · 2026Review
- Evaluation of Portulaca oleracea (Purslane) extract as a natural anticoccidial agent in japanese quails: Effects on growth performance, immune response, and gut health.Poultry science · 2026Article
- Shilajit as a Natural Product from Sedimentary Rocks: Biological Origin and Antioxidant Properties.Biochemical genetics · 2026Article
- Lathyrane Diterpenoids: Half-Century of Chemical Insights and Therapeutic Potential.Plants (Basel, Switzerland) · 2026Review
- Phenolic and Terpenic Composition ofPlants (Basel, Switzerland) · 2026Article
- The Mevalonate Pathway: Innovations, Applications, and Challenges in Biotechnology with Emphasis on Fungal Biology.Journal of fungi (Basel, Switzerland) · 2026Review
- Assessment of the Acute Toxicity and Anxiolytic-Like Effect of α-Humulene in Adult Zebrafish (Danio rerio).Chemistry & biodiversity · 2026Article
- Sesquiterpene-rich Root Essential Oil of Nardostachys jatamansi Exhibits Antiproliferative and Pro-apoptotic Activity in Colon Cancer Cells.Applied biochemistry and biotechnology · 2026Article
- Natural Bioactive Compounds in Polycystic Ovary Syndrome: Properties, Molecular Mechanisms, and Therapeutic Potential.International journal of molecular sciences · 2026Review
- Medicinal Plants as Biopesticides Against Pests and Diseases of Maize (Plants (Basel, Switzerland) · 2026Review
- Advances in Natural Product Extraction: Established and Emerging Technologies.Molecules (Basel, Switzerland) · 2026Review
- Structural Modification of Selected Essential Oil Components for Potential Anticancer Applications: A Review.Pharmaceuticals (Basel, Switzerland) · 2026Review
- The Chemopreventive and Anticancer Potential of Glucosinolates and Their Hydrolysis Products from Cruciferous Vegetables.Nutrients · 2026Review
- Identification of Antioxidant, Antimicrobial, and Cytotoxic Compounds From Hymenocardia acida Tul. Using Ultra-High-Performance Liquid Chromatography-Quadrupole Exactive-Orbitrap-Mass Spectrometry and Molecular Networking Approach.Chemistry & biodiversity · 2026Article
- Recent advances in cassane diterpenoids: structural diversity and biological activities.RSC advances · 2026Review
- Review
- Article
- Targeting Ferroptosis in Sepsis: Therapeutic Potential and Mechanisms of Natural Products and Traditional Chinese Medicine.Journal of inflammation research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Terpenes are among the most diverse kinds of natural products because of their remarkable chemical variety. Numerous biological characteristics of terpenoids have been documented, including their antibacterial, antifungal, antiviral, antihyperglycemic, anti-inflammatory, and antiparasitic effects, as well as their cancer chemopreventive benefits. Additionally, terpenes are utilized in the manufacturing of organic solvents, varnishes, inks, adhesives, synthetic polymers, natural rubbers, cleaning supplies, biofuels, insecticides, and food and beverage items. Terpenes are therefore highly valued in modern medicine, pharmacy, nutraceuticals, cosmetics, and other fields. Plant oils, including terpenes, have been used to treat a variety of diseases without a full understanding of the roles or modes of action of particular bioactive substances. Many of these compounds are only present in nature in extremely small amounts; thus, methods such as metabolic engineering and synthetic biology are used to harvest them in large quantities in order to produce enough medicine. This comprehensive review aims to elucidate the biochemistry, phytochemical properties, and pharmacological activities of terpenes in metabolic disorders.
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