Evidence map›Paper›PMID 40458766›Full record

ArticleJHLT open2025

Infant lung transplantation: First German experience including two cases of ABO blood group incompatible transplantations.

Anna Katharina Zürn, Nicolaus Schwerk, Carsten Müller, Gregor Warnecke, Jawad Salman, Michael Sasse, Harald Köditz, Thomas Jack, Bettina Bohnhorst, Gesine Hansen and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Anna Katharina ZürnDepartment of Pediatric Pneumology Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
Nicolaus SchwerkDepartment of Pediatric Pneumology Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
Carsten MüllerDepartment of Pediatric Pneumology Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
Gregor WarneckeDepartment of Cardiac Surgery, University Hospital of Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Jawad SalmanDepartment of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Michael SasseDepartment of Pediatric Cardiology and Critical Care Medicine, Hannover Medical School, Hannover, Germany.
Harald KöditzDepartment of Pediatric Cardiology and Critical Care Medicine, Hannover Medical School, Hannover, Germany.
Thomas JackDepartment of Pediatric Cardiology and Critical Care Medicine, Hannover Medical School, Hannover, Germany.
Bettina BohnhorstDepartment of Pediatric Pneumology Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
Gesine HansenDepartment of Pediatric Pneumology Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
Oliver KeilClinic of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
Katja NickelClinic of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
Dmitry BobylevDepartment of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Fabio IusDepartment of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Julia CarlensDepartment of Pediatric Pneumology Allergology and Neonatology, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infant lung transplantation (LuTx) has been rarely performed in Europe and poses unique challenges. Methods: We reviewed referrals for LuTx to our center for patients below 1 year of age from January 1, 2018 to December 31, 2022. Clinical data and outcomes of transplanted infants and data on patients who were declined for evaluation, not listed after evaluation, or died before LuTx were collected. The number of donor lungs from organ donors younger than 1 year of age offered to our center and their utilization were analyzed for the same time period. Results: A total of 18 referrals were analyzed. Ten referrals were declined; 2 had contraindications to transplant and 2 infants died after full evaluation. A total of 4 infants (median age 185 days, range 85-225; mean weight 6063 g, standard deviation [SD] ±438 g) underwent bilateral LuTx after a mean waiting time of 52, SD ±43 days. Underlying diseases included surfactant protein deficiencies ( Conclusions: Our longitudinal analysis highlights the high pre-LuTx morbidity of infants with respiratory failure and challenges associated with timely evaluation and listing. Nevertheless, infant LuTx shows promising results in selected candidates, including ABO blood group incompatible transplantations.

Indexed as

ABO incompatible transplantationdonor lungsGermanyinfantlung transplantation

Identifiers

PMID40458766
PMCPMC12127578

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.