Evidence map›Paper›PMID 40458741›Full record

ArticlePatient preference and adherence2025

Predictors of Topical Corticosteroid Adherence Among Caregivers of Children with Atopic Eczema.

Elaine Li Fong Liew, Noraida Mohamed Shah, Wei Wen Chong, Latha R Selvarajah, Ummi Syahida Sulaiman, Nirmala Ponnuthurai

Abstract read
In one paragraph

Article in Patient preference and adherence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Corticosteroid Phobia in Patients with Atopic Dermatitis: A Narrative Review.Clinical, cosmetic and investigational dermatology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elaine Li Fong LiewCentre of Quality Management of Medicine, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Campus, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Kuala Lumpur, 50300, Malaysia.
Noraida Mohamed ShahCentre of Quality Management of Medicine, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Campus, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Kuala Lumpur, 50300, Malaysia.ORCID 0000-0002-2509-4213
Wei Wen ChongCentre of Quality Management of Medicine, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Campus, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Kuala Lumpur, 50300, Malaysia.ORCID 0000-0002-6036-8478
Latha R SelvarajahDermatology Department, Hospital Sultan Ismail, Jalan Persiaran Mutiara Emas Utama, Taman Mount Austin, Johor Bahru, 81100, Malaysia.
Ummi Syahida SulaimanCentre of Quality Management of Medicine, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Campus, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Kuala Lumpur, 50300, Malaysia.
Nirmala PonnuthuraiPediatric Dermatology Unit, Pediatric Department, Hospital Tunku Azizah, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Kuala Lumpur, 50300, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Poor adherence to topical treatment regimens is linked to treatment failure and results in using systemic agents with more toxic effects. Studies on the factors that affect caregivers' adherence, especially in using topical corticosteroid (TCS) are still lacking. This study aims to determine the adherence score to TCS among caregivers of children with atopic eczema (AE) and the predictors of their adherence. Patient and Methods: Caregivers of children with AE who used TCS in the past three months at the dermatology clinic of two major hospitals were recruited to complete a self-reported survey on the child's eczema severity, degree of TCS phobia using TOPICOP© and caregivers' adherence to TCS using a 12-item medication adherence scale. Multiple linear regression was utilised to determine the predictors of caregivers' adherence. Results: Responses were received from 121 caregivers, with mean age of 35.9 years (SD ± 5.43) and 73.6% (n = 89) were females. The mean global TOPICOP© score was 25.4% (SD ± 14.5) and the mean adherence score was 48.5 (SD ± 6.6; maximum score = 60). Severe eczema (B = 4.330, CI 1.907 to 6.754, p < 0.001) and those who do not know the name of their child's medication (B = 6.922, CI 2.126 to 11.718, p < 0.05) were positive predictors of TCS adherence. TCS phobia was a negative predictor of TCS adherence (B = -0.300, CI -0.449 to -0.510, p < 0.001). Conclusion: Caregivers of children with AE showed good adherence score towards TCS use. Addressing TCS phobia may improve TCS adherence among caregivers of children with AE.

Indexed as

atopic eczemacaregiverspredictorstopical corticosteroid adherencetopical corticosteroid phobia

Identifiers

PMID40458741
PMCPMC12129009

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.