In Silico, In Vitro, and In Vivo Investigations of Anticancer Properties of a Novel Platinum (II) Complex and Its PLGA Encapsulated Form.

Zahra Shabaninejad, Mahdiyar Dehshiri, Sayed Mostafa Modarres Mousavi, Maryam Nikkhah, Sadegh Shirian, Sajad Moradi, S Masoud Nabavizadeh

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In one paragraph

Article in Bioinorganic chemistry and applications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zahra ShabaninejadDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box 14115-154, Tehran, Iran.ORCID https://orcid.org/0000-0003-0983-7416

Mahdiyar DehshiriDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box 14115-154, Tehran, Iran.ORCID https://orcid.org/0009-0003-3643-3692

Sayed Mostafa Modarres MousaviDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box 14115-154, Tehran, Iran.ORCID https://orcid.org/0000-0002-8685-4298

Maryam NikkhahDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box 14115-154, Tehran, Iran.ORCID https://orcid.org/0000-0003-0744-2699

Sadegh ShirianDepartment of Pathology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.ORCID https://orcid.org/0000-0003-4137-9056

Sajad MoradiNano Drug Delivery Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, P.O. Box 7616913555, Kermanshah, Iran.ORCID https://orcid.org/0000-0001-8500-1931

S Masoud NabavizadehDepartment of Chemistry, College of Sciences, Shiraz University, P.O. Box 84334-71946, Shiraz, Iran.ORCID https://orcid.org/0000-0003-3976-7869

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the development of multinuclear platinum complexes has introduced a new era in platinum-based chemotherapy, offering improved cytotoxicity and the ability to overcome resistance. However, these complexes still face challenges related to water solubility, biodistribution, and targeted delivery. This study provides a comprehensive investigation of a novel platinum (II) complex, [Pt

Indexed as

antitumorapoptosisnanoencapsulationplatinum complexPLGA

Identifiers

PMID40458703

DOI10.1155/bca/2673015

PMCPMC12127131

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.